background: the present study aimed to survey antileishmanial activity of methanolic holothuria leucospilota extract against leishmania major promastigotes in vitro. methods: promastigotes were cultured in rpmi 1640 and after reaching the stationary phase, the study was conducted with different concentrations of the extract. afterwards, mtt colorimetric assay for the obtaining of 50% inhibitory...

sphingolipids (GSLs) from echinoderms, a series of studies on the isolation and structural elucidation of the GSLs from sea cucumber species have been performed in our laboratory. In the study of the GSLs of the sea cucumber Holothuria pervicax, we reported the isolation and structure of ten glucocerebrosides revealing a very close resemblance in structure. However, all these compounds still ex...

The sea cucumber with the Latin name Holothuria scabra has high economic value. This leads to overfishing in nature. One of areas Bangka Belitung Islands Province that produces sand cucumbers is Coastal Village Batu Aer, Simpang Pesak District, East Regency. problems faced by partners at this time are: 1) Partners do not have skills manage cultivation business, because they still catch from nat...

Facing an alarming continuing decline of wild sea cucumber resources, management strategies were developed over the past three decades to sustainably promote development, maintenance, or regeneration fisheries. In New Caledonia (South Pacific), dedicated efforts via restocking and ranching programs implemented cope with overharvesting sandfish Holothuria scabra recent loss known populations. or...