NF-κB activation induced by lipopolysaccharide (LPS) in cultured hepatic macrophages (HM) may be abrogated by pretreatment of cells with a lipophilic iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one (L1, deferiprone), suggesting a role for iron in this molecular event [M. Lin, M., R. A. Rippe, O. Niemelä, G. Brittenham, and H. Tsukamoto, Am. J. Physiol. 272 ( Gastrointest. Liver Physiol. 35): G...

The effects of modified heavy metal (HM) availability on the microbial community structure and on the microbe-mediated degradation of herbicide isoproturon (IPU) were evaluated in soil with a long-term HM contamination. The fate of C-ring labelled IPU was investigated for over 60 days under controlled microcosm conditions. Phosphate mineral apatite and a water solution of Pb, Zn, and Cd salts w...

BACKGROUND In the absence of human breast milk, infant and follow-on formulas can still promote efficient growth and development. However, infant formulas can differ in their nutritional value. OBJECTIVE The objective of this study was to compare the effects of human milk (HM) and infant formulas in human infants and a weanling rat model. METHODS In a 3 wk clinical randomized controlled tri...

BACKGROUND Glutamine and proline are metabolized the liver and may collaborate on its regeneration. Parenteral nutrition (PN) containing either glutamine or proline was given to partially hepatectomized rats. The total RNA content and growth factor gene expression in hepatic remnants was measured, to determine the effects of these amino acid supplementation on the expression of growth factors d...

ETHNOPHARMACOLOGICAL RELEVANCE Cancer patients in all cultures are high consumers of herbal medicines (HMs) usually as part of a regime consisting of several complementary and alternative medicine (CAM) modalities, but the type of patient, the reasons for choosing such HM-CAM regimes, and the benefits they perceive from taking them are poorly understood. There are also concerns that local infor...

We present full of the properties about HM(X). HM(X) is a general framework for Hindley/Milner type systems with constraints. Speciic type systems can be obtained by instantiating the constraint parameter X. For instance, the Hindley/Milner type system itself can be obtained by instantiating X to the Herbrand constraint system. We give a generic type infernce algorithm for HM(X) type systems. U...

BACKGROUND Improvements in antimetabolite drugs have prolonged the survival of patient with hematological malignancies. However, these drugs may have hepatotoxic side effects and may induce acute liver failure, chronic liver fibrosis, cirrhosis, or even hepatocellular carcinoma (HCC). Although liver resection remains a curative option for HCC, its role in HCC with hematological malignancies has...

The notes below will serve as the basis for the module lectures to be given on the topics of Jordan form, nonnegative matrices, and Markov chains. As you'll see, most of the proofs have been omitted in the notes. The intention is to sketch the proofs during the lectures, but also to have the students work through some of the details (using references such as those listed at the end of this docu...

Background: The population ageing occurring worldwide resulted in multiple researches on sedentary ageing and quality of life. Purpose: To verify the effects of a physical activity programme on the quality of life (QOL) of elderly individuals served by a governmental health programme. Design: Descriptive inquiry research. Methods: randomly distributing 70 elderly individuals in a control group ...

Using the dog as an experimental model, the relationship of the Thoracic Compression Reflex (TCR) to the Heimlich Maneuver (HM) was examined. TCR was equally effective as lateral chest compression in relieving artificially induced choke. Destruction of the TCR by vagotomy rendered relief of choke by HM ineffectual in 5 of 8 dogs. It was concluded TCR may be a factor in HM, but that mechanical c...