نتایج جستجو برای: hla تایپینگ
تعداد نتایج: 40195 فیلتر نتایج به سال:
conclusions aih in our region presents with advanced disease affecting predominantly children and adolescents. there is a genetic association of hla dr6 along with other alleles and antigens in our patients with aih. objectives the aim of this study was to evaluate the clinical profile of autoimmune hepatitis (aih), and determine the associated antigens and alleles by performing hla typing. pat...
Background: Erythropoietin (EPO) was first known as a factor for red blood cell proliferation and differentiation. New studies show the effects of EPO on immune system. Objective: In this study, the effects of pretreatment with recombinant human erythropoietin (rHuEPO) on the anti-human leukocyte antibody (anti-HLA) titer were determined. Methods: Three groups of rats were sensitized with human...
background: thalassemia is probably the most common single gene disorder causing a major public health problem in the world. currently, allogenic hematopoietic stem cell transplantation (hsct) is the only curative therapy for thalassemia. one major limitation of hsct is the lack of hla-identical sibling donors, so attention has turned to finding phenotypically matched unrelated donors. patients...
چکید ه سابقه و هدف سیستم HLA نقش کلیدی در فرار سلولهای سرطانی از سیستم ایمنی ایفا میکند. AML سرطان رده میلوئیدی سلولهای خونی است که با رشد سریع سلولهای سفید غیر طبیعی در مغز استخوان شناخته میشود. مطالعههای متعدد در سراسر جهان ارتباط AML با آللهای HLA را بررسی نمودهاند. این مطالعه با هدف بررسی ارتباط بین آللهای HLA-A,-B,-DRB1 و بیماری AML در استان کرمان انجام شد. مواد و روشها ...
Background: Different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis B (HB) vaccine do not produce protective levels of anti-HB antibody, a phenomenon which could be linked to certain human leukocyte an-tigen (HLA) class-II alleles or haplotypes. Objectives: The present study was under-taken to determine the frequency of HLA class-II alleles in ...
Background & Objective: Unexplained recurrent spontaneous abortion (URSA) is defined as an unknown cause of occurrence of three or more clinically detectable pregnancy losses before 20 weeks of gestation, but it occurs presumably as a result of the immune system dysfunctions. We supposed that the disruption of semen or spermatozoa might be responsible for the dysfunction of the...
چکید ه سابقه و هدف با توجه به تاسیس مرکز پذیرش اهداکنندگان سلول های بنیادی خونساز در سازمان انتقال خون ایران (مرکز سپاس) در سال 1387, بر آن شدیم به بررسی آنتی ژن های سازگاری بافتی داوطلبان اهدای این سلول ها از قومیت های حاضر در شهر تهران طی سال 91-90 بپردازیم. مواد و روش ها در یک مطالعه توصیفی، 1513 نفر از افراد داوطلب عضو مرکز سپاس در محدوده سنی 18 تا 50 سال و با سابقه یک بار اهدای خون...
introduction: recognition of human leukocyte antigens (hla) is of importance for hematopoietic stem cell transplantation. any hla-mismatches between the donor and recipient can cause graft rejection or other complications. in hla-typing experiments, usage of hla-known reference cells accompany with hla-unknown samples is obligatory. some international centers represent these cells with high exp...
the association of hla class ii genes with ulcerative colitis (uc) as an autoimmune disease has been investigated for several years. however, factors responsible for genetic predisposition of this disease have so far not been clearly understood. in this study, for the first time, we aimed to investigate the association between hla-drb1 types and uc in the population of kerman, a city southeast ...
ABSTRACT : In the course of HLA typing for the members of 102 families who had referred for bone marrow and kidney transplantation to the tissue typing laboratory in Aliasghar Hospital, Isfahan ,between the years 1371 -1375 (1992-96),we found a case of crossing over in HLA System in a family. The fourth child of this family showed a crossing over brtween HLA -A and HAL -B Locous . The HLA phe...
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