this study was carried out as a pilot project in imam-khotneini, a teaching general hospital mainly dealing with cases of reconstructive surgery. the age of onset! geographical distribution, histologic type and other features ofskin cancer in iran were determined. the most coftutloll neoplasm in both sexes was bee the age group 0/65 and over had higher rate of acquired skin cancers. east aiarbu...

BACKGROUND Chronic recurrent sinusitis (CRS) is one of the most common chronic conditions in the United States. There is a significant subpopulation of CRS patients who remain resistant to cure despite rigorous treatment regimens including surgery, allergy therapy, and prolonged antibiotic therapy. Antimicrobial photodynamic therapy (aPDT) is a noninvasive nonantibiotic broad spectrum antimicro...

Abstract Background In ulcerative colitis (UC), persistent histological activity is associated with higher rates of relapse and long-term complications, even when endoscopic remission achieved; therefore, healing a potentially important treatment target. Etrasimod an investigational, once-daily, oral, selective sphingosine 1-phosphate receptor 1,4,5 (S1P1,4,5) modulator for the moderately to se...

STUDY DESIGN An in vivo study to develop a goat large-animal model for intervertebral disc (IVD) degeneration. OBJECTIVE To determine an optimal method for inducing goat IVD degeneration suitable for testing disc regeneration therapies. SUMMARY OF BACKGROUND DATA Although rodent, rabbit, and other small animal studies are useful, the narrow dimensions of IVDs in these species limit studies ...

There are inherent problems with the endoscopic and pathologic criteria for columnar-lined esophagus (CLE). Furthermore, the clinical and biological significance of an irregular squamocolumnar junction (SCJ) is unclear. The aim of this study was to evaluate the association between histologic features in SCJ biopsies and CLE and to gain insight into the significance of an irregular SCJ. The stud...

although the diagnostic category of atypical squamous cells of undetermined significance (ascus) has been known since 1988, its use and appropriate clinical follow up and management still remains controversial. this study was carried out to evaluate the diagnostic value of ascus, using cytohistologic correlation. a retrospective review of archival materials in our cytology laboratory files was ...

abstract: adequate processing of tissues before histologic slices is necessary for preparation of proper histologic sections in animal studies. fixation is one of the most important and early laboratory stages of tissue processing. amount of penetration time of fixator material, into deep layers and central portions of hard tissues, is important factor for prevention of cell lysis. the purpose ...