نتایج جستجو برای: hila mutant
تعداد نتایج: 129793 فیلتر نتایج به سال:
Background: The methylotrophic yeast Pichia pastoris is an appealing production host for a variety of recombinant, including biologics. In this sense, various genetic- and non-genetic-based techniques have been implemented to improve the production efficiency of this expression platform. Los1 (loss of supression) encodes a non-essential nuclear tRNA exporter in Saccharomyces cerevisiae, which i...
Introduction: Human papillomavirus (HPV) 16 E7 protein is expressed constitutively by HPV-infected tumor cells. Mutant versions of E7 are considered as safer candidates for immunotherapy of cervical cancer. Different strategies including formulation with adjuvants are used to induce a potent immune response against antigenic proteins. Methods: In this experimental study, we used Escherichia co...
Background and purpose: Due to the high annual birth rate of thalassemia major in our country, its prevention by prenatal diagnosis is of important priority. Gene mutation remains unknown in 10-20% of thalassemia trait people in Iran. In these cases, linkage analysis using polymorphic sites which are located near or within the gene is necessary to follow the mutant or the normal chromosome. Ssp...
There is limited literature that examines villages in the perspective of destination attractiveness. The purpose this research to 1) describe tourism potential village; 2) analyse role stakeholders promoting village as a destination; 3) steps or efforts develop from A qualitative approach guides author analysing attractiveness destinations Hila village. Data collection was carried out through i...
in order to increase tylosin production by streptomyces fradiae, two mutagens, i. e. uv and ems (ethylmethanesulfonate) were used. death curves were plotted for these mutagens. optimum condition for obtaining mutants by uv radiation was determined by using a uv source lamp at a distance of 20 cm for 40-60 seconds. when ems was used at 4% (w/v) concentration, the best mutants were isolated after...
Abstract OBJECTIVES Histone gene mutant malignant gliomas - H3K27-altered diffuse midline glioma (DMG) and hemispheric (DHG) H3G34-mutant occur in all age groups can have significant variation clinical outcomes. Here, we report comprehensive genomic profiling from one of the largest collections H3F3A-mutant analyzed to date, identifying subsets defined by recurrently co-mutated genes. METHODS W...
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