Objective(s): Phytochemicals such as polyphenols, alkaloids, and terpenoids, protect against the development of early stages and complications of diabetes mellitus according to various reports. The aim of this study was to measure the anti-dyslipidemic and anti-diabetic effects of Citral on high-fat-diet (HFD) and streptozotocin (STZ) induced diabetic dyslipidemic rats and to see also its effec...

The effect of Pediococcus acidilactici M76 (lactic acid bacteria) isolated from makgeolli on mice fed a high fat diet was investigated to clarify the lipid lowering function. C57BL/6J male mice were randomly divided into a normal diet (ND) group, high fat diet (HD) group, HD plus Pediococcus acidilactici DSM 20284 reference strain (PR) group, and HD plus Pediococcus acidilactici M76 strain (PA)...

People who supplement their diets with extra zinc usually have potentially harmful changes in lipoprotein metabolism. Because zinc can interfere with copper metabolism and copper deficiency has produced similar changes in lipid metabolism in animals and people, the hypothesis that lipid alterations from high zinc intakes are accompanied by changes in copper metabolism was tested. Progenies of s...

In this study, selectively bred rainbow trout (Oncorhynchus mykiss) with improved fillet yield were reared on three commercially available diets that varied in dietary lipid content: low (LL, 18%), moderate (ML, 24%), and high (HL, 29%–33%). The objective was to determine if a genotype by diet interaction affects product muscle quality traits (HY) (LY) lines of trout. Main effects the genetic l...

a major function of the enterocytes is absorption, processing, and export of dietary lipids into the lymphatic system. pluronic l-81 is a non-ionic hydrophobic surfactant, which specifically inhibits lipid absorption in the intestine when administered in vivo. this compound is therefore an attractive probe to perturb and investigate the molecular and intracellular events in chylomicron assembly...

Abstract In this paper we present an investigation of parental-diet-driven metabolic programming in offspring using a novel computational network analysis tool. The impact high paternal carbohydrate intake on offsprings’ phospholipid and triglyceride metabolism F1 F2 generations is described. Detailed lipid profiles were acquired from neonate (3 weeks), adult (16 weeks) serum, liver, brain, hea...

Lemon (Citrus limon) contains various bioactive flavonoids, and prevents obesity and obesity-associated metabolic diseases. We focused on eriocitrin (eriodictyol 7-rutinoside), a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. To investigate the mechanism of action of eriocitrin, we conducted feeding experiments on zebrafish with diet-induc...

Anti-atherosclerosis effects of perilla oil were investigated, in comparison with lovastatin, in rabbits fed a high-cholesterol diet (HCD). Hypercholesterolemia was induced in rabbits by feeding the HCD containing 0.5% cholesterol and 1% corn oil, and perilla oil (0.1 or 0.3%) was added to the diet containing 0.5% cholesterol for 10 weeks. HCD greatly increased blood total cholesterol and low-d...

BACKGROUND/AIM Hypercholesterolemia plays an important role in the development of atherosclerotic disease, which is one of the leading causes of mortality in the world. Previous studies showed that cyclooxygenase (COX) inhibitors could be used in treating hypercholesterolemia. Thepresentstudywas designed to testwhether COX-2 inhibition can improve lipid profiles inhypercholesterolemia. MATERI...

cardiovascular disease (cvd) due to atherosclerosis is the foremost cause of premature mortality and of disability-adjusted life years (dalys) in developed and developing countries (1).  the associated mortality is  preventable through treatment of dyslipidemia (2). over half of the first chd events and 3/4 of chd deaths are preventable by controlling the risk factors, including diet, exercise,...