نتایج جستجو برای: high grade glioma

تعداد نتایج: 2202508  

2016
Jinbai Huang Jing Luo Weibing Wang Chunping Mao Yao Zhang Tao Yang

The present study is to investigate the differences in Ki-67 expression and microvessel density (MVD) among cerebral schistosomiasis, low grade gliomas and high grade gliomas. Expressions of Ki-67 and CD34 in surgical specimens from 12 cases of cerebral schistosomiasis lesions, 12 cases of low grade gliomas and 12 cases of high grade glioma were detected by streptavidin-perosidase immunohistoch...

Journal: :AJNR. American journal of neuroradiology 2007
S K Ellika R Jain S C Patel L Scarpace L R Schultz J P Rock T Mikkelsen

BACKGROUND AND PURPOSE Perfusion imaging using CT can provide additional information about tumor vascularity and angiogenesis for characterizing gliomas. The purpose of our study was to demonstrate the usefulness of various perfusion CT (PCT) parameters in assessing the grade of treatment-naïve gliomas and also to compare it with conventional MR imaging features. MATERIALS AND METHODS PCT was...

Journal: :International Journal of Radiation Oncology*Biology*Physics 2019

Journal: :Cell 2016
Michele Ceccarelli Floris P. Barthel Tathiane M. Malta Thais S. Sabedot Sofie R. Salama Bradley A. Murray Olena Morozova Yulia Newton Amie Radenbaugh Stefano M. Pagnotta Samreen Anjum Jiguang Wang Ganiraju Manyam Pietro Zoppoli Shiyun Ling Arjun A. Rao Mia Grifford Andrew D. Cherniack Hailei Zhang Laila Poisson Carlos Gilberto Carlotti Daniela Pretti da Cunha Tirapelli Arvind Rao Tom Mikkelsen Ching C. Lau W. K. Alfred Yung Raul Rabadan Jason Huse Daniel J. Brat Norman L. Lehman Jill S. Barnholtz-Sloan Siyuan Zheng Kenneth Hess Ganesh Rao Matthew Meyerson Rameen Beroukhim Lee Cooper Rehan Akbani Margaret Wrensch David Haussler Kenneth D. Aldape Peter W. Laird David H. Gutmann Houtan Noushmehr Antonio Iavarone Roel G.W. Verhaak

Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic glioma driving alterations and suboptimal disease classification. We defined the complete set of genes associated with 1,122 diffuse grade II-III-IV gliomas from The Cancer Genome Atlas and used molecular profiles to improve disease classification, identify molecular correlations, and provide insights in...

2016
Maria Beatrice Morelli Massimo Nabissi Consuelo Amantini Daniele Tomassoni Francesco Rossi Claudio Cardinali Matteo Santoni Antonietta Arcella Maria Antonietta Oliva Angela Santoni Carlo Polidori Maria Paola Mariani Giorgio Santoni

The Transient Receptor Potential (TRP) superfamily consists of cation-selective and non-selective ion channels playing an important role both in sensory physiology and in physiopathology in several complex diseases including cancers. Among TRP family, the mucolipin (TRPML1, -2, and -3) channels represent a distinct subfamily of endosome/lysosome Ca2+ channel proteins. Loss-of-function mutations...

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