By introducing long carbon-chain alkyl groups at the C-13 position of berberine and palmatine, 13-n-hexyl/13-n-octyl berberine and palmatine chloride analogues 4a-d were synthesized and examined by MTT assays for cytotoxic activity in seven human cancer cell lines (7701QGY, SMMC7721, HepG2, CEM, CEM/VCR, KIII, Lewis), yielding IC₅₀ values of 0.02 ± 0.01-13.58 ± 2.84 μM. 13-n-Octyl palmatine (co...

P. J. Skabara WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, UK E-mail: [email protected] D. J. Crouch School of Chemistry, University of Manchester, Manchester M13 9PL, UK M. Heeney Department of Materials, Queen Mary, University of London, London E1 4NS, UK I. McCulloch Department of Chemistry, Imperial College London, London SW7 2AZ, U...

In the title compound, C15H22N2OS2, the di-thio-carbazate group adopts an EE conformation with respect to the C=N bond of the benzyl-idene moiety. The hexyl side chain adopts an extended conformation and the C-S-C-C torsion angle is -93.36 (13)°. In the crystal, inversion dimers linked by pairs of N-H⋯S hydrogen bonds generate R 2 (2)(8) loops.

In the title structure, [CoRu(C(5)H(5))(C(17)H(26)P)(2)Cl]PF(6), the Ru(II) atom is bonded to a cyclo-penta-dienyl ring, a Cl atom and two P atoms of the chelating 1,1'-bis-(dicyclo-hexyl-phosphino)cobaltocenium (di-cypc) ligand, leading to a three-legged piano-stool coordination. Part of the PF(6) (-) counter-anion is disordered over two positions, with a site-occupancy ratio of 0.898 (7):0.10...

Hexi Corridor is an excellent region for high-quality wines in China, but the characteristic and style of red wine from this unclear. To elucidate regional Corridor, aroma properties made 16 different varieties/clones grapes were comprehensively analyzed using HS-SPME-GC-MS, sensory evaluation, odor activity value method, partial least squares regression analyses. We identified 52 compounds fou...

The aim of this qualitative study is to analyse the role in-branch efforts banks on migrating customers from branch banking digital in India. In-depth semi-structured interviews were conducted with bank executives representing senior management public and private sector Qualitative content analysis technique was used data. Varieties responses received during clubbed into four main themes based ...

The optical properties of two series of thiophene-based polymers are interpreted by torsion analysis. When approached by the calculated HOMO/LUMO energy gaps of model molecules, the wavelength shifts from solutions to films are reasonable in cyclohexyl-substituted series but not in hexyl-substituted series, indicating that solid packing force plays a more important role in the former than in th...