نتایج جستجو برای: hereditary spherocytosis
تعداد نتایج: 84467 فیلتر نتایج به سال:
INTRODUCTION Sickle cell anemia and thalassemia result in impaired bone health in both adults and youths. Children with other types of chronic hemolytic anemia may also display impaired bone health. STUDY DESIGN To assess bone health in pediatric patients with chronic hemolytic anemia, a cross-sectional study was conducted involving 45 patients with different forms of hemolytic anemia (i.e., ...
The mammalian erythrocyte depends on a complex glycolytic mechanism for most of its energy. It is believed that this mechanism controls the transfer of cations across the cell membrane, and serves to maintain the biconcave shape of the red blood cell. Adenosine triphosphate and 2,3-diphosphoglycerate participate in the energy exchanges involved in these processes (1-9). Alterations in the relat...
INTRODUCTION Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. The exact mechanism of this development is still unknown. We herein report a case of intrathoracic EMH, manifesting as a posterior mediastinal tumor in a patient with hereditary spherocytosis. PRESENTATION OF CASE A 45-year-old ma...
We present evidence that the hereditable hemolytic disease, hereditary spherocytosis (HS), involves an abnormality in protein of the red cell membrane. Unlike that from normal red cells, lipid-free proteins extracted from HS red cell membranes fail to increase in sedimentation rate when treated with cations; such treatment of normal membrane proteins has been shown by others to cause the format...
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