background: this study was carried out to observe the radioprotective effects of rosemarinus officinalis leaves extract (roe) against radiation-induced histopathological alterations in liver of mice. materials and methods: adult swiss albino mice were exposed to 6 gy gamma radiation in the presence (experimental) or absence (control) of roe to study the qualitative and quantitative alterations ...

 The implementation of autonomous vehicles involves an increase in the number and depth of system interactions in comparison to user-driven cars. There is a corresponding need to address the system safety implications of autonomy. Traditional hazard analysis techniques are not designed to identify hazardous states caused by system interactions. An emerging technique based on systems theory, Sy...

the purpose of this study was to examine the acute and sub-acute effects of diazinon onhistopathological parameters of liver tissue and blood level of hepatic enzymes of male commonfrog (rana ridibunda). frogs were assigned to 9 groups (n=8, meaning 8 frogs in each group):control and treatment groups with 30, 60, 90 and 120 μg/l diazinon in water for one day or oneweek. hepatic enzymes containi...

gastrointestinal (gi) and hepatic manifestations are not uncommon in patients with systemic lupus erythematosus (sle). they include nonspecific symptoms as well as serious, life-threatening complications necessitating urgent, aggressive therapy. in addition to direct involvement of the gi system by the disease, many drug-induced side effects and opportunistic infections have gi and hepatic mani...

how to cite this article: dara n, sayyari aa, imanzadeh f. hepatic encephalopathy: early diagnosis in pediatric patients with cirrhosis. iran j child neurol. 2014 winter; 8(1):1-11. objective as acute liver failure (alf) and chronic liver disease (cirrhosis) continue to increase in prevalence, we will see more cases of hepatic encephalopathy. primary care physician are often the first to suspec...

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Hepatitis C virus (HCV) infection has been associated with hepatic steatosis. However, the role of hepatic steatosis in the pathogenesis of HCV infection remains controversial. In our study, 425 consecutive HCV-viremic patients with biopsy-proven chronic hepatitis C (male, 264; mean age, 49.0 years) were enrolled. Scoring of hepatic steatosis was based on the method described by Kleiner and on ...

n-3 long chain polyunsaturated fatty acids (n-3LC-PUFA) are essential components of vertebrate membrane lipids and are now at critically low levels in modern Western diets. The main human dietary source for n-3LC-PUFA is fish and seafood, and over 50% of global fish production is currently supplied by aquaculture. However, increasing pressure to include vegetable oils, which are devoid of n-3LC...

Isoniazid (INH) remains a cornerstone key constitute of the current tuberculosis management strategy, but its hepatotoxic potentiality remains a significant clinical problem. Our previous findings succeed to establish a rat model of INH hepatotoxicity employing the inflammatory stress theory in which non-injurious doses of inflammatory-mediating agent bacterial lipopolysaccharides (LPS) augment...