BACKGROUND Curative hepatectomy with bile duct resection is the treatment for perihilar cholangiocarcinoma. A locally advanced tumor necessitates hepatectomy with simultaneous vascular resection, and reconstruction remains an obstacle for surgeons. Studies have focused on the variations of hepatic arteries. Nevertheless, the anatomical alignment of the portal veins, bile ducts, and hepatic arte...

Introduction: Hepatectomy is a standard treatment for hepatocellular carcinoma(HCC) patients. There paucity of data regarding the incidence and impact acute kidney injury(AKI) after hepatectomy. Method: This was retrospective study using prospectively maintained dataset. All consecutive HCC patients who underwent hepatectomy from 2003-2018 were analyzed. AKI defined as increase in serum creatin...

The incidence of breast metastasis from extramammary malignancy was rare. A case of breast metastasis from hepatocellular carcinoma (HCC) after partial hepatectomy and radical lymphadenectomy in a 49-year-old woman was reported. The breast metastasis from HCC was confirmed by immunohistochemistry. Therefore, metastatic breast HCC as end stage should be considered for patients who had liver canc...

Selective substrates and inhibitors have been used to measure kinases phosphorylating endogenous proteins in rat liver nuclei during growth and regeneration after partial hepatectomy. Peaks in activity were found at 5, 22, and 29 hours after partial hepatectomy. Administration of alpha 1 and beta adrenergic blockers suggested that the Be2+ sensitive and cyclic AMP-dependent protein kinases were...

Colon cancer is the second leading cause of cancer death in the United States. Patients with colon cancer metastatic to liver and bone are deemed non-curable and have a poor prognosis. We present a case of recurrent colon cancer with synchronous hepatic and bony metastases treated with radiation, chemotherapy, and curative-intent hepatectomy. The patient is alive and free of disease recurrence,...

The prognosis of gastric cancer patients with liver metastasis is very poor because many cases of gastric cancer with liver metastasis have multiple metastatic nodules in the liver and other non-curative factors, such as severe lymph node metastasis and/or peritoneal metastasis. The prognosis for gastric cancer patients with synchronous liver metastasis and the significance of hepatectomy inclu...

To determine the role of NK cells in regulation of tissue growth, the phenotype and function of liver-resident NK cells were studied after 70% partial hepatectomy in rats. The process of liver regeneration was generally completed by day 14. In contrast, the number of liver-resident NK cells (NKR-P1bright) was restored as early as day 3 after partial hepatectomy. However, spontaneous functions o...

When a large part of the liver of a mammal is removed, there follows, after a lag period,’ a dramatic increase in the number of hepatic cells making DNA. Partial hepatectomy has, for this reason, been commonly used to investigate the mechanisms that normally govern entry of a cell into the period of DNA formation. The liver appears to be informed immediately about the partial hepatectomy, and s...

BACKGROUND Liver resection for hepatocellular carcinoma (HCC) has the highest local controllability among all local treatments and results in a good survival rate. However, the recurrence rates of HCC continue to remain high even after curative hepatectomy. Moreover, it has been reported that some patients with HCC have an early death due to recurrence. We analyzed the preoperative risk factors...