نتایج جستجو برای: hemoglobinopathy
تعداد نتایج: 519 فیلتر نتایج به سال:
A delayed fetal-to-adult hemoglobin (Hb) switch ameliorates the severity of β-thalassemia and sickle cell disease. The molecular mechanism underlying the epigenetic dysregulation of the switch is unclear. To explore the potential cis-variants responsible for the Hb switching, we systematically analyzed an 80-kb region spanning the β-globin cluster using capture-based next-generation sequencing ...
OBJECTIVE More than 75% of Indian toddlers are anemic. Data on factors associated with anemia in India are limited. The objective of this study was to determine biological, nutritional, and socioeconomic risk factors for anemia in this vulnerable age group. METHODS We conducted a cross-sectional study of children aged 12 to 23 months in 2 rural districts of Karnataka, India. Children were exc...
OBJECTIVE The Turkish Society of Pediatric Hematology set up a National Hemoglobinopathy Registry to demonstrate the demographic and disease characteristics of patients and assess the efficacy of a hemoglobinopathy control program (HCP) over 10 years in Turkey. MATERIALS AND METHODS A total of 2046 patients from 27 thalassemia centers were registered, of which 1988 were eligible for analysis....
Patients with hemoglobinopathy may experience short-term benefits from nutritional support and blood transfusions, but long-term results be better if a precise diagnosis is obtained course of treatment or safety measures adopted. The goal the study to determine prevalence haemoglobin abnormalities in people who presented moderate severe anaemia using electrophoresis They will undergo tes...
From 2010 to 2020, we investigated 197 children with hemolytic anemia of unknown etiology at the Dmitry Rogachev National Medical Research Center Pediatric Hematology, Oncology and Immunology Ministry Healthcare Russian Federation. Fifty-four them were found have hemoglobinopathy caused by unstable abnormal hemoglobins: Hb Monroe/Kairouan, Tacoma, Köln/SanFrancisco, Cheverly, City Hope, Southam...
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