نتایج جستجو برای: hematological malignancy

تعداد نتایج: 81838  

2011
Angelos Kyriacou Nolan Arulraj Haren Varia

INTRODUCTION Spontaneous splenic rupture is well recognized in the context of hematological malignancies (lymphoproliferative and myeloproliferative disorders); a few case reports have also linked solid tumors, such as pancreatic and liver cancer, with the occurrence of spontaneous splenic rupture. This is the first case report of lung cancer as a likely cause of spontaneous splenic rupture. ...

2015
Hongli Zhao Liyuan Guo Hong Zhao Jiaxin Zhao Hao Weng Bin Zhao

C-X-C chemokine receptor 4 (CXCR4) is frequently over-expressed in various types of cancer; many agents against CXCR4 are in clinical development currently despite variable data for the prognostic impact of CXCR4 expression. Here eighty-five studies with a total of 11,032 subjects were included to explore the association between CXCR4 and progression-free survival (PFS) or overall survival (OS)...

2017
Benjamin W. Teh Simon J. Harrison Cody Charles Allison Monica A. Slavin Tim Spelman Leon J. Worth Karin A. Thursky David Ritchie Marc Pellegrini

BACKGROUND A translational study in patients with myeloma to determine the utility of immune profiling to predict infection risk in patients with hematological malignancy was conducted. METHODS Baseline, end of induction, and maintenance peripheral blood mononuclear cells from 40 patients were evaluated. Immune cell populations and cytokines released from 1 × 106 cells/ml cultured in the pres...

Journal: :Planta medica 2017
Mark E Issa Sylvian Cretton Muriel Cuendet

Multiple myeloma is characterized by the accumulation of malignant plasma cells in the bone marrow. Multiple myeloma is the second most frequently diagnosed hematological malignancy, predominantly affecting the elderly. Despite recent advances in the development of novel therapies, multiple myeloma remains an incurable malignancy where the majority of patients relapse, develop resistance, and e...

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