Infections of the central nervous system (CNS) are infrequently diagnosed in immunocompetent patients, but they do occur in a significant proportion of patients with hematological disorders. In particular, patients undergoing allogeneic hematopoietic stem-cell transplantation carry a high risk for CNS infections of up to 15%. Fungi and Toxoplasma gondii are the predominant causative agents. The...

Abstract Background In patients with infectious diseases, disseminated intravascular coagulation (DIC) is often diagnosed without the fibrinogen value. The relationship between hypofibrinogenemia and outcomes of DIC in diseases has thus remained unclear. Methods We analyzed 3204 who received thrombomodulin alfa (TM-?) for suspected DIC. Hypofibrinogenemia was defined by a level < 1.5 g/L. Re...

É. Azoulay (ed.), Pulmonary Involvement in Patients with Hematological Malignancies, DOI: 10.1007/978-3-642-15742-4_2, © Springer-Verlag Berlin Heidelberg 2011 Acute pulmonary events are among the most common complications in patients with hematological malignancies. These events often raise difficult diagnostic and therapeutic challenges. In this book, readers faced with these challenges will ...

Gene transfer into the hematopoietic stem cell has shown curative potential for a variety of hematological disorders. Primary immunodeficiency diseases have led to the way in this field of gene therapy as an example and a model. Clinical results from the past 15 years have shown that significant improvement and even cure can be achieved for diseases such as X-linked severe combined immunodefici...

In addition to a few disorders such as acute T-cell leukemia that are typically associated with the human T-cell leukemia virus (HTLV) 1 in endemic regions, this virus may also play a role in some other hematological diseases. Here, we examine the incidence of HTLV in hematological diseases from a nonendemic region in central Europe. Data obtained by PCR and/or serological techniques from a tot...

  This study was done to investigate of some hematological and biochemical factors of rainbow trout (Oncorhynchus mykiss ) fry in west of Mazandaran in Iran. About 50 pools of blood samples from diseased fry were collected within 30 months from November 2002 till March 2005 from three hatchery farms in western part of Mazanderan province. In addition 30 pools of blood samples as control group w...

Studies have shown that different exercise ways are of the most important factors that affect cardiovascular risk factors and hematological parameters. This present paper aims to study the effects of two methods of endurance and resistance training on lipid profiles, heart rate, and hematological parameters in obese male students. 36 obese students were purposefully selected and randomly divi...

Cytochrome P450 2J2 (CYP2J2) epoxygenase converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EETs) that exert multiple biological effects in the cardiovascular system and in various human solid cancers. However, it is unknown whether this enzyme is expressed or plays any role in malignant hematological diseases. In this study, we found strong and highly selective CYP2J2 e...

Hematological Malignancies Diana Vilar-Compte, MD, MSc; Alejandro Garcia-Horton, MD; Alejandra Pamela Gonzalez-Rodriguez, BSc; Alejandra Solis-Flores, MD; Miguel Garcia-Leon, MSc; Patricia Cornejo-Juarez, MD, MSc; Patricia Volkow, MD; Jose Ignacio Santos-Preciado, MD; Rosa Maria Wong Chew, MD DSc; Infectious Diseases, Instituto Nacional de Cancerología, Mexico City, Mexico; Experimental Medicin...

Aspirate and bone marrow biopsy are diagnostic methods used in the study of hematological diseases allowing molecular, cytogenetic, and immunophenotype analyses, indispensable today for the classification of hematolymphoid malignancies. Its indications are ample and include various types of hematolymphoid malignancies, solid tumors, study of fever of unknown origin, and other infiltrative disea...