نتایج جستجو برای: hematologic abnormalities
تعداد نتایج: 122867 فیلتر نتایج به سال:
Neonatal lupus erythematosus is a very rare disease, clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart block. Generally, when patients have skin manifestations, they have no cardiac defects and vice-versa; however, in 10% of cases these manifestations may coexist. Other findings may include hematologic, hepatic and ne...
Exogenous estrogens used for therapeutic purposes or endogenous estrogen sources such as functional Sertoli cell or ovarian granulosa cell tumors may cause bone marrow toxicity in dogs. The condition is characterized by hematologic abnormalities including thrombocytopenia, anemia, and leukocytosis or leukopenia. Despite intensive therapy with blood or platelet-rich transfusions, broad-spectrum ...
Extra-adrenal myelolipomas are rare, generally solitary, non-functioning tumors consisting of adipose tissue and hematopoetic elements. These lesions are not known to be associated with underlying hematologic disorders or documented bone marrow abnormalities. We describe the extremely rare occurrence of multifocal, extra-adrenal myelolipomas in a 35-yr-old male. A markedly hypocellular bone mar...
Myelodysplastic syndrome (MDS) is cytogenetically heterogeneous and retains variable risk for acute myeloid leukemia transformation. Though not yet fully understood, there is an association between genetic abnormalities and defects in gene expression. The functional role for infrequent cytogenetic alteration remains unclear. An uncommon chromosomic abnormality is the presence of the Philadelphi...
BACKGROUND Kala-azar is a multisystem infection of the reticuloendothelial system. Various hematologic abnormalities have been described in kala-azar including hemophagocytic syndrome (HPS). METHODS We reviewed bone marrow aspirate smears from 18 documented cases of kala-azar complicated by HPS. RESULTS The bone marrow smears were hypercellular with erythroid hyperplasia. Megaloblastic ch...
To determine if certain transient monocular visual loss patterns predict the associated vascular abnormalities, we prospectively evaluated 100 consecutive patients. Each patient had hematologic tests, a carotid artery study (arteriography in 74, duplex ultrasonography in the remaining 26), and an ophthalmologic examination. Patients with altitudinal or lateralized transient monocular visual los...
OBJECTIVE To describe a case of vitamin B(12) deficiency with classic and rare clinical features and novel radiographic features. DESIGN Case report. SETTING Johns Hopkins Hospital neurology service. PATIENT Middle-aged man with neuropathy, myelopathy,impaired cognition, and extrapyramidal signs. RESULTS The patient had neurologic and hematologic signs of vitamin B(12) deficiency, with ...
Abstract Background While antifungal consumption in immunocompromised patients appears high, data on children are limited. We analyzed use hospitalized across Europe order to better organize a European pediatric stewardship programs (pAFS). Methods A multicenter 12-wk modified point-prevalence study was conducted. All hematology-oncology (HO) or bone marrow/solid organ transplant (BMT/SOT) unit...
Clinical and biochemical manifestations of lecithin-cholesterol acyltransferase (LCAT) deficiency include an abnormal lipid profile (characterized by hypercholesterolemia with markedly decreased high-density lipoprotein cholesterol [HDL-C] and hypertriglyceridemia), corneal opacities, hematologic abnormalities (normochromic anemia of varying intensity), splenomegaly, variable early coronary art...
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