Cinefluorographic analysis of mitral valve motion in intact clogs provided evidence that the motility of the valve cusps is restrained by tension exerted through the chordae tendineae throughout the cardiac cycle, except for the rapid filling phase. At the onset of ventricular systole, early contraction of the papillary muscles may play an important role in approximating the mitral valve cusps....

Seven patients have been described who developed a third heart sound in association with a paravalvar leak around a Starr-Edwards mitral valve prosthesis. These patients had all had the mitral valve cusps, chordae tendineae, and part of the papillary muscles excised. The presence of a third heart sound in them supports the concept of Potain (I900) that the third heart sound arises by vibrations...

Heart valve replacement is fast becoming a routine surgery worldwide, and heart valve prostheses are today considered among the most widely used cardiovascular devices. Mechanical and bioprostheses have been the traditional choices to the replacement surgeries. However, such valves continue to expose patients to risks including thrombosis, infection and limited valve durability. In recent years...

BACKGROUND In middle income countries, the burden of rheumatic heart disease (RHD) remains high, but the prevalence of other heart valve diseases may rise as the population life expectancy increases. Here, we compared population-based data on surgical procedures to assess the relative importance of causes of heart valve disease in Salvador, Brazil. METHODOLOGY/PRINCIPAL FINDINGS Medical chart...

From 1982 till 1999, our department performed a total of 2970 heart valve replacements--92% of which were with mechanical heart valves. During this period, there were 8 patients who came to our department with mechanical heart valve obstruction. All these patients presented with signs of heart failure or compromised haemodynamic. Confirmatory tests included transthoracic or transoesophageal ech...

This report deals with a rare complication of disc-valve prosthesis in the mitral area. A significant disc poppet and struts destruction of mitral BeaU valve prostheses occurred 20 and 17 months after implantation. The resulting valve incompetence in the first case contributed to the death of the patient. The durability of Teflon prosthetic valves appears to be in question and this type of valv...

Infective endocarditis (IE) is the infection of endocardial surface heart. IE rare disease with significant complications which require early diagnosis and proper treatment for reducing morbidity mortality.IE vegetation on pulmonary valve, leaflets are uncommon. However, we have diagnosed one case infective associated Multisystem Inflammatory Syndrome in Children (MIS-C) related COVID-19. MIS-C...

BACKGROUND Specialist clinics are recommended for the assessment and follow-up of patients with heart valve disease. We sought to identify the current provision of specialist valve clinics in UK. METHODS A database of all UK National Health Service hospitals was created. An online survey was distributed to each hospital to examine the model of heart valve clinic, patient population, provision...

BACKGROUND Various complications lead to reoperation in patients who undergo prosthetic valve replacement where inflammatory process could be involved. The goals of this study were to identify risk factors that correlate with reoperation in patients with prosthetic heart valves and to investigate the relationship between reoperation and inflammatory gene polymorphisms. RESULTS The study inclu...

BACKGROUND Minimal data exist on the long-term survival of dialysis patients after cardiac valve surgery. Current practice guidelines of the American College of Cardiology/American Heart Association Task Force on the management of patients with valvular heart disease proscribe the use of bioprosthetic (tissue) valves in hemodialysis patients. METHODS AND RESULTS Dialysis patients hospitalized...