The heart makes its living by liberating energy from a variety of oxidizable substrates, either simultaneously or vicariously.1 Because of built-in mechanisms that choose the most efficient substrate for a given physiological environment, the heart is a true metabolic omnivore.2 The link between metabolism and function of the heart was discovered by Langendorff3 when he demonstrated that the ma...

Major burn injury results in impairment of left ventricular (LV) contractile function. There is strong evidence to support the involvement of gut-derived factor(s) transported in mesenteric lymph in the development of burn-related contractile dysfunction; i.e., mesenteric lymph duct ligation (LDL) prevents burn-related contractile depression. However, the cellular mechanisms for altered myocard...

Background Accurate total body surface area burned (TBSAB) estimation is a crucial aspect of early burn management. It helps guide resuscitation and is essential in the calculation of fluid requirements. Conventional methods of estimation can often lead to large discrepancies in burn percentage estimation. We aim to compare a new method of TBSAB estimation using a three-dimensional smart-phone ...

Burns are considered one of the most common and shocking forms of trauma. Patients with serious thermal or electrical injury necessitate immediate specialized care to minimize morbidity and mortality. Electrical burns and burn injuries caused by fire, hot liquids, and contact with hot surfaces, have been recognized as a significant and major public health problem in most developing countries. B...

This study addresses maternal and foetal complications in pregnant women hospitalized for burn injuries in 2003-2008. It was a retrospective descriptive cross-sectional study, carried out in pregnant women hospitalized in the burn ward of Imam- Khomeini Hospital, Iran, in 2003-2008 (burn injury rate, 1.88%, 39 cases; mean age, 23.51 ± 4.78 yr). The pregnant woman death rate was 66.7%: 26 patien...

and disfiguring forms of trauma, as it affects the skin, the largest andmost visible organ. The National Burn Care Review (British Burn Association, 2001) determined that as many as 500,000 people suffer a burn injury each year in the UK. Most are minor. Around 13,000 people, of which 45% are children, are admitted to hospital; only a small proportion have severe injuries requiring resuscitatio...

It is estimated that burn injury affects about 1 in 3000 people annually world-wide. Burn injury induces severe pain, which is difficult to control in the great majority of cases making burn injury-associated pain a serious clinical challenge. In order to meet this clinical need, novel targets should be identified. Like pain developing in other peripheral pathologies, burn injury-associated pai...

Delayed gastric emptying is common following severe large cutaneous burns; however, the mechanisms of burn-induced delayed gastric emptying remain unknown. The aim of this study was to explore the possible involvement of hyperglycemia and cyclooxygenase-2 receptors in the burn-induced gastric dysrhythmias. Gastric slow waves and gastric emptying were assessed in rats 6 h following sham or burn ...

Introduction: Epidemiological study on burn injuries and exploration of the risk factors in different settings is important for effective intervention. Very little is known about burn injuries in Ethiopia. Objectives: The aims of this study were to assess the annual incidence of burn injuries and to describe the local knowledge about burns in Mekele town in Tigray, Ethiopia. Methodology: We did...

BACKGROUND Burns are one of the most important causes of traumatic death in children worldwide. A pediatric burn center was established in our hospital in August 2009. The aim of this study was to compare patient profiles and data before and after the burn treatment center was established. METHODS Burn patients were admitted to the pediatric surgery department between January 2005 and August ...