We present the case of a 68-year-old female patient with exertional dyspnea, mild pretibial oedema and echocardiographically verified enlarged left atrium, but preserved ventricular systolic function normal filling pressures at rest. NT-proBNP values were within reference values. The diastolic stress echocardiographic test confirms presence heart failure ejection fraction (HFpEF). This report r...

OBJECTIVE Thrombin, the final coagulation product of the coagulation cascade, has been demonstrated to have many physiological effects, including pro-fibrotic actions via protease-activated receptor (PAR)-1. Recent investigations have demonstrated that activation of the cardiac local coagulation system was associated with atrial fibrillation. However, the distribution of thrombin in the heart, ...

Human superior and inferior venae cavae at the orifices to hearts obtained from two cadavers were histologically examined with regard to the distribution of cardiac muscle fibers in their walls. The superior vena cava contained cardiac muscle fibers together with smooth muscle fibers. The cardiac muscle fibers were distributed uninterruptedly from the atrium to the root of the azygos vein, cove...

SELECTIVE angiocardiography of the left side of the heart is of prime importance for the accurate preoperative diagnosis of those lesions involving the mitral valve, ventricular septum, outflow tract of the left ventricle, or the aorta itself. The injection of contrast medium into the pulmonary artery for the demonstration of the left atrium and left ventricle is less satisfactory than the dire...

Similar expression patterns of mRNA profiles for Endothelin 1 (ET-1) and Thrombospondin 1 (TSP1) from GeneAtlas U133A, gcrma, suggest that these two mediators are dominantly synthesized in the myocard and lungs. This paper proposes that intertraffic of these two mediators between myocard and lungs via pulmonary and coronary vessels optimizes cardiopulmonary functions and maintains their tissue ...

background: accidents are the second reason for mortality and morbidity in iran. among them, brain injuries are the most important damage. clarification of the effects of brain injuries on different body systems will help physicians to prioritize their treatment strategies. in this study, the effect of pure brain trauma on the cardiovascular system and lungs 24 hours post trauma was assessed. m...

CMAJ • FEBRUARY 23, 2010 • 182(3) © 2010 Canadian Medical Association or its licensors E147 An 84-year-old woman with a history of atrial fibrillation presented with cough, lethargy and symptoms of progressive heart failure. She had not seen a physician for many years, despite persistent symptoms. Physical examination showed an elevated jugular venous pressure, a grade 2/6 holosystolic murmur a...

Highlights Intravascular leiomyoma with heart extension is a rare occurring condition. According to the available data, number of cases does not exceed 30 despite many years studies. Often cardiac hospitals cannot establish clinical picture, so surgeon removes only tumors, which inevitably leads recurrence tumor after few months. Abstract Leiomyomatosis an extremely disease that occurs in women...