The aim of this study was to compare three strategies for intensity-modulated radiotherapy (IMRT) for 20 head-and-neck cancer patients. For simultaneous integrated boost (SIB), doses were 66 and 54 Gy in 30 fractions for PTVboost and PTVelective, respectively. Two-phase IMRT delivered 50 Gy in 25 fractions to PTVelective in the First Plan, and 20 Gy in 10 fractions to PTVboost in the Second Pla...

In the Netherlands, about 2,300 people per year are diagnosed with a malignant tumor in the head and neck region. About 450 of them are referred to the Radboud University Nijmegen Medical Centre. Most of them undergo radiotherapy, either as a sole treatment, or in combination with surgery or chemotherapy. As part of the tailored radiation therapy most patients will be treated with Intensity Mod...

Knowledge-Based IMRT Treatment Planning for Bilateral Head and Neck Cancer by Matthew Charles Schmidt Graduate Program in Medical Physics Duke University Date:_______________________ Approved: ___________________________ Shiva K. Das, Co-Supervisor ___________________________ Joseph Y. Lo, Co-Supervisor ___________________________ Robert Reiman, Jr. An abstract of a Thesis submitted in partial ...

In patients with head and neck cancer, the most common issue after radiation treatment is xerostomia consequences of that, which are affecting quality everyday life patient. Subjectively manifested as dryness in oral cavity, followed obstructed chewing swallowing food. Mostly it happens because death cells gland that supposed to be dividing, caused by radiation. To improve patients’ treatment, ...

 Background: To analyze the dosimetric and radio biologic advantages between intensity modulated radiotherapy (IMRT) and 3 dimensional conformal radiotherapy (3DCRT) and selection of optimal photon energy for IMRT treatments. Material and methods: 24 patients with localized prostate carcinoma were planned for 3DCRT and IMRT techniques. Radiation dose of 54 Gy with 2 Gy/fraction, was planned to ...

Intensity-modulated radiotherapy (IMRT) for complex sites such as tumors of the head and neck requires a level of accuracy in dose calculation beyond that currently used for conformal treatment planning. Recent advances in treatment planning systems have aimed to improve the dose calculation accuracy by improving the modeling of machine characteristics such as interleaf leakage, tongue and groo...

Abbreviations: NPC: Nasopharyngeal Carcinoma; NACT: Neoadjuvant Chemotherapy; 5y-OS: 5-Year Overall Survival; 5y-DFS: 5-Year Disease-Free Survival; 5y-RFS: 5-Year Local-RecurrenceFree Survival; 5y-MFS: 5-Year Distant-Metastasis-Free Survival; IMRT: Intensity-Modulated Radiation Therapy; CCT: Concurrent Chemotherapy; HN-MRI: Magnetic Resonance Imaging of Head and Neck; G3/4: Grade 3 To 4; CTCAE ...

Accurate estimation of the surface dose in radiotherapy patients with head and neck cancer is very important terms treatment. The aim this study to evaluate for intensity-modulated (IMRT) using thermoluminescent dosimeters (TLDs). In addition, it aimed examine estimates treatment planning system (TPS) different grid sizes. Before computed tomography (CT) images were taken 15 patients, 5 points ...

IMPORTANCE Approximately 50% of head and neck cancer survivors experience dysphagia and related morbidity. Intensity-modulated radiation therapy (IMRT) is increasingly used to treat oropharyngeal cancers with excellent oncologic outcomes, but few studies have compared it with conventional 3-dimensional conformal radiation therapy (3D-CRT) to determine whether it can decrease treatment-related t...