نتایج جستجو برای: hdm 4

تعداد نتایج: 1304326  

Journal: :Thorax 2012
Belinda J Hales Lee Ying Chai Claire E Elliot Leigh J Pearce Guicheng Zhang Tatjana K Heinrich Wendy-Anne Smith Merci M Kusel Patrick G Holt Peter D Sly Wayne R Thomas

BACKGROUND Infants who develop house dust mite (HDM) allergy and HDM-sensitised children with severe persistent asthma have low antibody responses to the P6 antigen of Haemophilus influenzae. OBJECTIVE To measure the development of antibody to two ubiquitous bacteria of the respiratory mucosa in a prospective birth cohort at high risk of allergic disease and to assess which responses are asso...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2011
Timothy D Le Cras Thomas H Acciani Elizabeth M Mushaben Elizabeth L Kramer Patricia A Pastura William D Hardie Thomas R Korfhagen Umasundari Sivaprasad Mark Ericksen Aaron M Gibson Michael J Holtzman Jeffrey A Whitsett Gurjit K Khurana Hershey

Increases in the epidermal growth factor receptor (EGFR) have been associated with the severity of airway thickening in chronic asthmatic subjects, and EGFR signaling is induced by asthma-related cytokines and inflammation. The goal of this study was to determine the role of EGFR signaling in a chronic allergic model of asthma and specifically in epithelial cells, which are increasingly recogni...

Journal: :International Journal of Transportation Science and Technology 2015

Journal: :European Journal of Operational Research 2008
Hongyi Chen Dundar F. Kocaoglu

In this paper, a comprehensive algorithm is developed to analyze the sensitivity of hierarchical decision models (HDM), including the analytic hierarchy process and its variants, to single and multiple changes in the local contribution matrices at any level of the decision hierarchy. The algorithm is applicable to all HDM that use an additive function to derive the overall contribution vector. ...

2015
J. Wu M. C. F. Prosperi A. Simpson E. M. Hollams P. D. Sly A. Custovic P. G. Holt

BACKGROUND Models that incorporate patterns of multiple cytokine responses to allergens, rather than individual cytokine production, may better predict sensitization and asthma. OBJECTIVE To characterize the patterns of peripheral blood mononuclear cells' (PBMCs) cytokine responses to house dust mite (HDM) allergens among children from two population-based birth cohorts using machine learning...

2017
Bobby W. S. Li Ralph Stadhouders Marjolein J. W. de Bruijn Melanie Lukkes Dior M. J. M. Beerens Maarten D. Brem Alex KleinJan Ingrid Bergen Heleen Vroman Mirjam Kool Wilfred F. J. van IJcken Tata Nageswara Rao Hans Jörg Fehling Rudi W. Hendriks

Group 2 innate lymphoid cells (ILC2) are implicated in allergic asthma as an early innate source of the type 2 cytokines IL-5 and IL-13. However, their induction in house dust mite (HDM)-mediated airway inflammation additionally requires T cell activation. It is currently unknown whether phenotypic differences exist between ILC2s that are activated in a T cell-dependent or T cell-independent fa...

A Taher Pour F Shafi Khani H Ansarin

Background and aim: Atopic dermatitis (AD) is a chronic relapsing skin disease that commonly begins during infancy and early childhood. Research studies refers to a relationship between exacerbation of atopic dermatitis and exposure to house dust mite (HDM), but the role of HDM in the pathogenesis of AD is controversial. The objecitve of this study was to assess the correlation of density...

Journal: :Journal of Investigative Dermatology 2023

The role of allergen in T-cell mediated IL-31 production and its relationship with clinical features atopic dermatitis (AD) is unknown. by T cells has been mainly analysed qRT-PCR intracellular flow cytometry polyclonal activated peripheral blood mononuclear a low number patients without association the clinic. We studied memory response to house dust mite (HDM) when cocultured autologous lesio...

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