BACKGROUND Cardiovascular disease is the leading cause of death and disability in older people. There is little information about the distributions of risk factors in older populations. This article describes the distribution and correlates of lipoprotein lipids in people greater than or equal to 65 years old. METHODS AND RESULTS Lipoprotein lipid concentrations were measured in 2,106 men (M)...

Glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD) is a minor HDL-associated protein. Because many minor HDL-associated proteins exchange between different lipoprotein classes during the postprandial state and are also involved in triglyceride (TG) metabolism, we hypothesized that GPI-PLD may play a role in the metabolism of TG-rich lipoproteins. To test this hypothesis, we examine...

OBJECTIVE untreated periodontal disease seems to cause low grade systemic inflammation and blood lipid alteration leading to increased cardiovascular disease risk. To start testing this hypothesis in colombian patients, a multicentre study was conducted including the three main state capitals: bogota, medellin and cali. METHODS in this study 192 (28.4%) advanced and 256 (37.8%) moderate perio...

This cross sectional study includes 500 diabetic and 500 apparently healthy subjects. The aim of the study was to compare anthropometric variables and lipid profile in diabetic and non-diabetics. Anthropometric variables included were height, weight, body mass index (BMI), waist hip ratio (WHR) and lipid parameters were serum total cholesterol (TC), triglycerides (TG), Low density lipoproteins-...

Loss of ABCA1 activity in Tangier disease (TD) is associated with abnormal apoB lipoprotein (Lp) metabolism in addition to the complete absence of high density lipoprotein (HDL). We used hepatocyte-specific ABCA1 knock-out (HSKO) mice to test the hypothesis that hepatic ABCA1 plays dual roles in regulating Lp metabolism and nascent HDL formation. HSKO mice recapitulated the TD lipid phenotype w...

  Abstract   Background: obesity is directly related to dyslipidemia which contributes significantly   to the risk of coronary heart disease, a major cardiovascular disease and a serious   health problem. The aim of this study was to compare the effects of low calorie   diet and those of lovastatin on serum lipoproteins, apo B, homocysteine, and total antioxidant capacity (TAC) in hyperlipidemi...

introduction: type ii diabetes is one of the most prevalent endocrine diseases in the world that results from a combination of insulin resistance and ß-cell failure. regarding importance of nutritional factors in management of diabetes, this study was designed to explore the effect of sesame oil on blood glucose and lipid profile in type ii diabetic patients at yazd diabetes research center in ...

The objective of the study was to assess the association between plasma levels of lipoprotein(a) [Lp(a)] and the presence of angiographically defined coronary artery disease (aCAD). Patients (346 men and 184 women) undergoing selective coronary angiography (SCA) were classified into groups with positive [aCAD(+)] and negative [aCAD(-)] findings and their age, body mass index (BMI), waist circum...

Low plasma levels of total cholesterol (TC) with or without hypertriglyceridemia have been frequently described in a variety of hematologic disorders in which anemia is a prominent feature.2,3 It is well established that β-thalassemia is associated with changes in plasma lipids and lipoproteins. In β-thalassemia major, low cholesterol levels caused by a significant reduction of both low-density...

Current lipid management guidelines are focused on decreasing low-density lipoprotein (LDL-C) levels as the primary target for reducing coronary heart disease (CHD) risk. Yet, many recent studies suggest that low levels of high-density lipoprotein (HDL-C) are a major independent risk factor for cardiovascular diseases. According to several clinical trials, a 1% increase in HDL-C is associated w...