Hepatitis C virus (HCV) affects an estimated 3.5 million persons in the United States (1), making it the most common bloodborne infection in the country. Recent surveillance data showed increased rates of HCV infection among adolescents and adults who are predominantly white, live in nonurban areas, and have a history of injection drug use.* U.S. birth certificate data were used to analyze tren...

INTRODUCTION Hepatitis C virus (HCV) infection is a global health problem which can lead to liver cirrhosis or hepatocellular carcinoma in one-fifth of chronically infected patients. MATERIALS AND METHODS The study group consisted of 123 patients: 90 with HCV mono- and 33 with HIV/HCV co-infection, who were treated with pegylated interferon alfa (Peg-IFN-α) and ribavirin. We analyzed selected...

Chronic hepatitis C virus (HCV) infection has been dubbed the “silent epidemic” because the infection remains quiescent for years, even decades, before clinically significant symptoms appear. The majority of Americans currently living with chronic HCV infection were infected before testing for the virus in blood products began in the early 1990s; therefore, an “age wave” of HCV infection compli...

Hepatitis C virus (HCV) is a major public health problem with more than 130-180 million people infected worldwide. Several studies in different populations have reported the association of human leukocyte antigen (HLA) genotypes, and HCV viral load, and genotypes. The aim of this study was to investigate a possible association between HLA class I and II alleles in HCV-infected patients and heal...

Abstract: Viral hepatitis (Hepatitis B Virus (HBV) & Hepatitis C (HCV)) related liver disease is a leading cause of morbidity and mortality especially in the patients with advanced renal failure who are treated dialysis, this due to high number blood transfusion sessions and/or cross contamination from dialysis circuits. Aims Objectives: This study aimed determine prevalence HBV HCV infecti...

Background: Anti-hepatitis C virus (anti-HCV) is the only screening test being used in diagnosis of hepatitis C. In this study, we examined anti-HCV positivity rates our hospital. Objectives: The aim administering was to distinguish patients with infection from false reactive results. Methods: tests were performed at Fatih Sultan Mehmet Training and Research Hospital Istanbul, Turkey, between J...

BACKGROUND/AIM A novel fluorescent enzyme immunoassay (FEIA) for the detection and quantification of serum hepatitis C virus (HCV) core protein was developed. The aim of this study was to evaluate the relation among serum HCV core protein level, HCV RNA level, and HCV genotype in patients with chronic HCV infection. PATIENTS AND METHODS Serum HCV core protein, HCV RNA, HCV genotype were deter...

BACKGROUND India has large PWID (persons who inject drugs) population estimated at 177,000. PWIDs are at high risk for HIV, Hepatitis B (HBV) and Hepatitis C (HCV) infections. We report the prevalence of HIV, HBV and HCV infections and correlates of HIV-HCV co-infection among male PWIDs in Delhi. METHODS 3748 male PWIDs were recruited for a longitudinal HIV incidence study. Participants were ...

Hepatitis C Virus (HCV) is a major cause of chronic liver disease in humans infecting about 170 million individuals worldwide. Therefore, there is much interest to understand the biology of HCV infection and develop effective remedies. While, studies have provided some insights into HCV infection such as a critical role for the interactions between the viral component (HCV core protein) and a h...