Congenital chloride diarrhea (CCD) is a rare autosomal recessive disorder, characterized by watery stools with C1- concentration around 150 meq/liter. We have perfused the colon of three patients and their three healthy siblings with different salt solutions containing 36C1- to determine the nature of the colonic defect in CCD. In the controls, net absorption of Na+ and C1- occurred against ste...

Abstract Wetlands deliver many ecosystem services but are under continuous threat due to various anthropogenic activities. The present study has been carried out examine the suitability of Kusheshwar-Asthan wetland's water for agriculture. A total 57 samples were analyzed quality parameters like electrical conductivity, pH, temperature, dissolved oxygen (DO), major cations (Ca2+, Mg2+, Na+, K+)...

Calcitonin is known to stimulate Ca2+ reabsorption and natriuresis and to increase adenosine 3',5'-cyclic monophosphate levels in early distal tubule, but its effects on acid-base transport mechanisms are not well characterized in this segment. We found that recovery of cell pH (pH1) from an induced acid load (using NH4+) in single isolated segments of the initial portion ("bright") of the rabb...

Although increased Na+/H+ exchange (antiport) activity has been shown to precede both granulocytic and monocytic differentiation of HL60 cells, its requirement for this process remains controversial. We show here that, in the absence of HCO3-, the Na+/H+ exchanger is the predominant mechanism involved in rapid recovery of pHi from cytoplasmic acidosis; however, in the presence of HCO3-, other m...

This study was conducted to evaluate the quality of the groundwaters and the impact of geological units on these waters in Hastijan area. For this purpose, 11 samples of water resources have been collected with their appropriate dispersal. Physico-chemical parameters of Mn, Ni, Cd, Cu, Zn, As Fe, Cr, and ions K+, Na+,Ca2+, Mg2+, Cl-, So42-, Hco3- as well as indicators TH, TDS, EC, PH were deter...

This paper focuses on the study of aquifer Continental Terminal in south Saloum river. aims to participate knowledge physicochemical quality and help understand origins processes mineralization water (CT). Physicochemical treatments show an average pH 6.61 indicating a slightly acidic overall. The electrical conductivity varies between 37.4 12,320 μS·cm-1 with 729.3 μS·cm-1. High conductivities...

Mutations in SLC4A4, the gene encoding the electrogenic Na(+)-HCO3(-) cotransporter NBCe1, cause severe proximal renal tubular acidosis (pRTA), growth retardation, decreased IQ, and eye and teeth abnormalities. Among the known NBCe1 mutations, the disease-causing mechanism of the T485S (NBCe1-A numbering) mutation is intriguing because the substituted amino acid, serine, is structurally and che...

water quality is a worldwide problem which affects human beings lives fundamentally. water scarcity is intensified in result of quality deterioration. different factors such as population increase, economic development and water pollution could be considered as the origins of the problem. the study and forecasting of water quality is necessary to prevent serious water quality deteriorations in ...

The water spider (Argyroneta aquatic) is the only known to live a fully aquatic life. Therefore, it has been subject of series studies on various aspects its unique biology such as reproductive behavior, sexual dimorphism, physiology, genetics, and silk. However, there have relatively few hydroecology where spiders live. habitat in Eundae-ri, Yeoncheon for A. aquatica, globally rare species, So...