OBJECTIVE Adipose derived stem cells (ASCs), as one of the important stromal cells in the tumor microenvironment, are determined with immunomodulatory effects. The principle aim of this study was to evaluate the immunosuppressive effects of ASCs on natural killer (NK) cells. MATERIALS AND METHODS In this experimental study, we assessed the expressions of indolamine 2, 3-dioxygenase (IDO1), ID...

Reactive oxygen and nitrogen species (ROS/RNS) play a crucial role in inflammatory bowel disease (IBD) exacerbating the chronic inflammatory process. Endogenous and diet antioxidants can neutralize these compounds. The apple is widely consumed, with several antioxidant activity compounds. The present study evaluated the effects of concentrated apple extract (CAE) in acetic acid induced colitis....

This study used Nelore embryo donors to evaluate the effects of summer temperatures and humidity in a tropical area on embryo recovery. Seventeen cows were randomly assigned to three groups (G1, G2 and G3) as well as 28 heifers into four groups (G4, G5, G6 and G7), and underwent a consecutive 4 days superovulation protocol (day 0 to 3) and two artificial inseminations (AI; day 4 and 5). Cortiso...

The aim of this study was to determine the most appropriate months for applying albendazole (ABZ; oral suspension dose 20 mg/kg body weight) to sheep naturally infected with Dicrocoelium dendriticum and kept at pasture, in order to reduce parasite egg shedding to a minimum, mainly during the cold months and, as a result, decrease pasture contamination by viable eggs. Five animal groups (G), hom...

Poly(amidoamine) (PAMAM) dendrimer nanoparticles have been demonstrated to elicit a well defined cytotoxicological response from mammalian cell lines, the response increasing systematically with dendrimer generation and number of surface amino groups. In this work, using generation G4, G5, and G6 dendrimers, this systematic response is furthermore demonstrated for the generation of reactive oxy...

Background: In the recent years, pregnancy outcomes in women with primary chronic glomerulonephritis (CGN) have been encouraging despite increased incidence of complications and preterm birth. However, impact on CKD progression remains understudied.
 Aim: To evaluate effect postpartum period patients CGN.
 Materials methods: This was an observational longitudinal study. The study grou...

background: the people residing in coastal areas of visakhapatnam are mostly engaged in fishery, which is always been a physically demanding job, and numerous factors have direct or indirect impact on the health of fishermen; but, the data about their physical fitness or health status is quite scanty. thus, the present study was conducted to assess their cardiorespiratory fitness pattern, as we...

The new Ds hadronic modes and recent measurements which differ substantially from previous measurements are listed in Table 1. The decay mode T?OK*+ is analogous to the pK+ and iT”“K+ modes previously observed and is seen at a comparable rate to that of (9~. The existence of these KT? decays indicates that the strength of the internal W emission dia* grams is sizable. The ox++ mode is seen only...