El eczema de manos es un motivo de consulta muy frecuente en dermatología que obliga a un amplio diagnóstico diferencial entre el que se incluirían la dermatitis irritativa y alérgica de contacto, la dermatitis atópica, la psoriasis o la dermatomiositis. Ante un eczema de manos unilateral hay que descartar una tinea manum e investigar posibles causas de fotoeczema alérgico de contacto. Presenta...

BACKGROUND Stress is known to activate or exacerbate dermatoses, but the relationships between chronic stress, job-related stress and sickness absence among occupational hand eczema (OHE) patients are inadequately understood. AIMS To see whether chronic stress or burnout symptoms were associated with cumulative sickness absence in patients with OHE and to determine which factors predicted sic...

A 68-year-old non-atopic woman was referred with recurrent perioral and lip dermatitis and oedema of the oral mucosa following dental treatments. Prior to retirement, she had been working as an auxiliary nurse for 31 years. Throughout a normal workday, she had been using protective rubber gloves for more than 2h in total, and >20 pairs of protective gloves. At the time, she experienced fluctuat...

Longitudinal dose-response analyses of alitretinoin (an investigational agent in the US) were conducted to supplement results from phase III studies in severe, refractory chronic hand eczema, with objectives to address several outstanding development issues (e.g., optimal dose, possible factors affecting efficacy and/or tolerability). Models were fitted to the physicians' global assessment scor...