نتایج جستجو برای: hamp 6 pichpyzdh2o

تعداد نتایج: 956869  

Journal: :Clinical chemistry 2012
Jean-Christophe Deschemin Marc Foretz Benoit Viollet Sophie Vaulont

Hepcidin plays a central role in iron homeostasis and contributes to the pathogenesis of several disorders. Consequently, development of a clear understanding of hepcidin regulation in various pathophysiological conditions has been the subject of intensive research. Technical limitations, however, have limited the wide availability of assays for measuring this iron-regulatory hormone in human s...

2017

In this section we analyze the effect of payment reduction on borrower default. Using a regression discontinuity empirical strategy, we find that immediate payment reduction with no change in long-term obligations significantly reduces default. Our findings indicate that additional payment reduction is effective irrespective of a borrower’s payment-to-income ratio, which is contrary to the view...

Journal: :Acta haematologica 2012
Pauline L Lee Terry Gaasterland James C Barton

We report on a 46-year-old black man who resided in Alabama with normal transferrin saturation, mild hyperferritinemia, chronic hepatitis C, and 3+ iron in hepatocytes and Kupffer cells. Exome sequencing revealed heterozygosity for SLC40A1 D270V (exon 7, c.809A→T), a mutation previously reported only in 1 black patient with iron overload who resided in the Republic of South Africa. The present ...

Journal: :Journal of bacteriology 2007
Divya N Amin Barry L Taylor Mark S Johnson

The Aer receptor guides Escherichia coli to specific oxygen and energy-generating niches. The input sensor in Aer is a flavin adenine dinucleotide-binding PAS domain, which is separated from a HAMP/signaling output domain by two membrane-spanning segments that flank a short (four-amino-acid) periplasmic loop. In this study, we determined the overall membrane organization of Aer by introducing c...

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