312 www.thelancet.com Vol 388 July 23, 2016 Aspirin is considered an aff ordable and widely available, if only modestly eff ective, thromboprophylactic for secondary stroke prevention. The two large randomised controlled trials of aspirin in acute ischaemic stroke reported that aspirin reduced the odds of early recurrent stroke at 2–4 weeks by about 12% (odds ratio [OR] 0·88, 95% CI 0·79–0·97) ...