BACKGROUND For patients unable to receive heparin anticoagulation during haemodialysis, saline flushes to reduce circuit clotting are often the norm. Regional citrate anticoagulation (RCA) although effective is not used by many centres including in Singapore. We wanted to demonstrate the superiority and safety of a simple regional citrate anticoagulation regime, compared to saline flushes, for ...

BACKGROUND Beta(2)-microglobulin (beta(2)-M) is recognized as a surrogate marker of middle-molecule uraemic toxins and is a key component in the genesis of dialysis-associated amyloidosis. Few studies have evaluated the association of beta(2)-M levels with clinical outcome in dialyzed patients. METHODS The prognostic implication of serum beta(2)-M levels for the survival of haemodialysis pati...

BACKGROUND Coagulase-negative staphylococci (CoNS) are frequently encountered pathogens in hospital environment. Dialysis patients, often carrying central venous catheters, are prone to CoNS infections. Methicillin-resistant (MR) staphylococci in hospitals are resistant to multiple antibiotics and may cause an overall increase in the incidence of staphylococcal infections rather than simply rep...

BACKGROUND Chronic kidney disease (CKD) is increasing worldwide and can lead to end-stage renal disease (ESRD). OBJECTIVES Because few patients with ESRD in the Republic of Guinea have access to haemodialysis, we retrospectively evaluated the prevalence of CKD, ESRD and access to supportive therapies. PATIENTS AND METHODS 579 CKD patients (304 males; mean age: 44 ± 16 years) were admitted i...

Kidney failure is associated with modifications of liver enzymes leading to difficulties in the diagnosis disease this population. Hence our aim was toevaluate patients on maintenance haemodialysis (MHD).

A 39-year-old woman with end-stage renal disease, which was maintained on haemodialysis, developed secondary haemochromatosis after receiving blood transfusions and intravenous iron supplementation without sufficient serum ferritin concentration monitoring. The patient received intravenous deferoxamine three times a week, combined with high-dose recombinant human erythropoietin therapy and haem...

Key words: Trichosporon beigelii; haemodialysis; kidney disease with chronic renal insufficiency had fungaemia been treated by maintenance haemodialysis three times per week for 3 months before admission. He had progressive loss of consciousness and intermittent low grade fever before he was admitted to a local hospital

A uraemic patient undergoing chronic haemodialysis developed diffuse metastatic pulmonary calcification and died from acute respiratory insufficiency after renal transplantation. Thirteen similar cases previously published are reviewed, with emphasis on the clinical and anatomical features of such calcinosis. The pathogenesis of this calcification in patients on maintenance haemodialysis and so...

A patient with renal failure after carbon tetrachloride poisoning is presented. Haemodialysis was required and renal function recovered completely. Convalescence was complicated by the development of an infectious-mononucleosis-like syndrome. The aetiology of this condition is discussed. The present case is the first to be reported after haemodialysis and transfusion of blood stored for at leas...

Acute severe intoxication with carbamazepine is associated with seizures, coma and respiratory depression. Traditionally, charcoal haemoperfusion is used to remove the drug. We present a case of carbamazepine intoxication, successfully treated with three hours of high-flux haemodialysis. Thus, haemodialysis using high-flux membranes is a feasible and effective therapeutic option for carbamazepi...