This issue of Cancer Control highlights cancers unique to women with emphasis on gynecologic cancers. Gynecologic cancers are diagnosed in approximately 77,000 women per year in the United States. The most common sites of gynecologic carcinomas, in order of increasing incidence, are the cervix, the ovaries, and the endometrium, all of which are profoundly affected in both the normal and maligna...

PURPOSE The methylation status of hMLH1, CDKN2A, and MGMT was investigated in a panel of synchronous cancers of the ovary and endometrium, fulfilling the clinicopathologic criteria for independent primary tumors to define the possible role of epigenetic mechanisms in the development of these cancers. EXPERIMENTAL DESIGN Bisulfite-converted DNA from 31 tumors (13 endometrial and 18 ovarian car...

We were exited to read the article by Carolyn Johnston et al. published in a recent issue of Gynecologic Oncology Reports. (Johnston et al., 2017). After the introductory paragraph the authors describe, in the following six sections of the manuscript, their views on different gynecologic oncology training programs in different parts of the world. The information for this study, the authors ment...

OBJECTIVE Frozen section is an accurate diagnostic tool with some unavoidable pitfalls in gynecologic tumors. We aimed to evaluate the diagnostic value of frozen section, and to detect the factors causing erroneous diagnosis in ovarian tumors. MATERIAL AND METHOD Frozen section and paraffin section reports of 282 patients with ovarian neoplasms diagnosed between July 2006 and January 2013 in ...

INTRODUCTION Ovarian teratomas undergo the malignant transformation in 0.2-2% of cases. The behavior of malignancies in mature cystic teratomas (MCT) is determined by their phenotype and not their derivation from germ cells. We can recognize pure angiosarcomas or as a part of other tumors like malignant mixed Mullerian tumors and adenosarcomas. PRESENTATION OF CASE We present the first case o...

Objective: In this study, we aimed to determine the learning curve for liver wedge resection performed as part of cytoreductive surgery in advanced ovarian malignant tumors. Materials and methods: This was a retrospective analysis 120 women diagnosed with stage IIIC cancer according International Federation Gynecology Obstetrics (FIGO) classification: 22 underwent (Group A), while 98 did not re...