The evolution of uricoteley as a mechanism for hepatic ammonia detoxication in vertebrates required targeting of glutamine synthetase (GS) to liver mitochondria in the sauropsid line of descent leading to the squamate reptiles and archosaurs. Previous studies have shown that in birds and crocodilians, sole survivors of the archosaurian line, hepatic GS is translated without a transient, N-termi...

introduction: in the current study, we compared the h-indices of web of science (wos), scopus, and gs of the iranian nuclear medicine scientists methods: full time members of two major nuclear medicine research centers of iran with more than 5 year of experience (nuclear medicine research center of mashhad university of medical sciences, and research institute for nuclear medicine of tehran uni...

introduction: in the current study, we compared the h-indices of web of science (wos), scopus, and gs of the iranian nuclear medicine scientists methods: full time members of two major nuclear medicine research centers of iran with more than 5 year of experience (nuclear medicine research center of mashhad university of medical sciences, and research institute for nuclear medicine of tehran uni...

partially fed (4 -5 days) h .a. anatolicum (iranian isolate) female adult ticks were used for preparation of antigens of midgut which are, the gut supernate antigen (gs), gut membrane antigen (gm), triton extracted gut membrane antigen ( tx-gm ) and sodium dodecyl sulphate treated triton extracted gut membrane antigen (sds-tx-gm). the new zealand white rabbits were immunized with gs, gm, tx- gm...

Introduction: In the current study, we compared the h-indices of Web of Science (WOS), SCOPUS, and GS of the Iranian nuclear medicine scientists Methods: Full time members of two major nuclear medicine research centers of Iran with more than 5 year of experience (Nuclear Medicine Research Center of Mashhad University of Medical Sciences, and Research Institute for Nuclear Medicine of Tehran Un...

Brassica sprouts contain abundant phytochemicals, especially glucosinolates (GSs). Various methods have been used to enhance GS content in sprouts. However, the molecular basis of GS metabolism in sprouts remains an open question. Here we employed RNA-seq analysis to compare the transcriptomes of high-GS (JL-08) and low-GS (JL-09) Brassica alboglabra sprouts. Paired-end Illumina RNA-seq reads w...

Maize (Zea mays L.) kernel pedicels, including vascular tissues, pedicel parenchyma, placento-chalazal tissue, and the surrounding pericarp, contained two forms of glutamine synthetase (EC 6.3.1.2), separable by anion exchange chromatography under mildly acidic conditions. The earlier-eluting activity (GS(p1)), but not the later-eluting activity (GS(p2)), was chromatographically distinct from t...

GS-9131 is a phosphonoamidate prodrug of the novel ribose-modified phosphonate nucleotide analog GS-9148 that demonstrates potent anti-human immunodeficiency virus type 1 (HIV-1) activity and an excellent resistance profile in vitro. Prodrug moieties were optimized for the efficient delivery of GS-9148 and its active diphosphate (DP) metabolite to lymphoid cells following oral administration. T...

The Gleason score (GS) of prostate cancer on diagnostic biopsies is an important parameter for therapeutic decision-making. Biopsy GS under-estimates the actual GS at radical prostatectomy in a significant number of patients due to samplingartifact. The aim of this study was to identify markers that are differentially expressed in Gleason grade 3 (GG3) tumor glands embedded in GS 4 + 3 = 7 and ...