Familial combined pituitary hormone deficiency is a rare endocrine disorder. We describe growth patterns of four children (3 females and 1 male) from two families with combined pituitary hormone deficiency. These children received growth hormone at ages ranging from 14.5 years to 19 years. While all the female siblings reached their target height, the male sibling was much shorter than mid pare...

Subject: Polycystic ovary syndrome (PCOS) is female disorder caused by cysts formation in ovarian that results of hormones secretion and menstrual cycle. Neuregulin 4 (NRG4) one adipokines family members synthesis release via adipose tissues, it acts as activator the epidermal growth factor receptor (EGFR).Objective Study: Assessment role NRG4 PCOS patients.Materials Methods: Present study incl...

Early erythroid precursor cells and myaloid progenitor cells (CFU-GM) from four patients with 5q syndrome ware cultured in order to study the in vitro growth patterns and to determine the clonal origin of this hamatologic disorder. Cultures of CFU-GM exhibited normal colony growth. while erythroid progenitor cells demonstrated a marked decrease or absence of colony growth. Chromosomal studas in...

Cornelia de Lange syndrome (CdLS) is a multisystem malformation syndrome. There is wide clinical variability in this disorder. This disorder is relatively uncommon and characterised by series of malformations which includes skeletal, craniofacial, gastrointestinal and cardiac malformations. The main clinical feature includes growth retardation, limb abnormalities, mental retardation, developmen...

Scanning tunneling spectroscopy at very low temperatures on homogeneously disordered superconducting titanium nitride thin films reveals strong spatial inhomogeneities of the superconducting gap Delta in the density of states. Upon increasing disorder, we observe suppression of the superconducting critical temperature Tc towards zero, enhancement of spatial fluctuations in Delta, and growth of ...

The roughening behavior of a one-dimensional interface fluctuating under quenched disorder growth is examined while keeping an anchored boundary. The latter introduces detailed balance conditions which allows for a simple but thorough analysis of equilibrium aspects at both macroscopic and microscopic scales. It is found that the interface roughens linearly with the substrate size only in the v...

Congenital malalignment of the great toenails is a disorder in which malalignment of the nail matrix results in angular lateral nail plate growth. The consequence is onychodystrophy, which may progress to onychogryphosis and chronic ingrown toenails. There has been debate as to whether the condition is inherited or acquired in utero secondary to improper fetal positioning. A 6-year-old boy and ...

Introduction. Primary cutaneous CD4+ lymphoproliferative disorder of small and medium cells (PC T-LPD small/medium cell) is a new entity identified in the WHO classification published 2017. The aim research was to characterize morphological immunohistochemical features PC cell. Materials methods. study examined 28 skin biopsies from 13 males 15 females with cell using histological Results. We d...