OBJECTIVE The aim of this study was to investigate whether the extent and topography of cerebral demyelination correlates with and predicts disease progression in patients with juvenile metachromatic leukodystrophy (MLD). METHODS A total of 137 MRIs of 46 patients with juvenile MLD were analyzed. Demyelination load and brain volume were quantified using the previously developed Software "clus...

PURPOSE This study investigated the correlation between isometric muscle strength, gross motor function, and gait parameters in patients with spastic cerebral palsy and to find which muscle groups play an important role for gait pattern in a flexed knee gait. MATERIALS AND METHODS Twenty-four ambulatory patients (mean age, 10.0 years) with spastic cerebral palsy who were scheduled for single ...

Standard physical therapy (SPT) with ground gait training is well recognized to improve the motor skill in cerebral palsy (CP) disease. Confirmation required on achieving better gross function partial body weight supported treadmill (PBWSTT). The objective of study analyze combination SPT PBWSTT for children spastic diplegic CP who able walk. A prospective design was conducted patients 2-7 year...

Assessing clinical change in motor function in children with cerebral palsy is a complex measurement task. Whereas a variety of methods have been developed to quantify specific aspects of gross motor behavior (eg, gait analysis, electrophysiological tests, energy-consumption techniques), systematic measurement of overall gross motor function is a more difficult problem. This special communicati...

Background: There is a plethora of literature with some conflicting findings on the effects implementing strength and/or aerobic training or circuit exercises to improve motor function children spastic hemiplegic cerebral palsy (CP). Circuit form body conditioning that involves endurance training, resistance high-intensity aerobics, and performed in circuit. Purpose: To investigate effect progr...

[Purpose] The purpose of this study was to examine the gross motor skill development of 5-year-old Kindergarten children in Myanmar. [Subjects and Methods] Total 472 healthy Kindergarten children (237 males, 235 females) of 2016-2017 academic year from four schools in urban area and four schools in rural area of Myanmar were recruited. The gross motor skill development of all subjects was asses...

Motor function, cognition, functional independence and quality of life have been described in myelomeningocele patients, but no study has investigated their relationships. We aimed to investigate the relationships between motor function, cognition, functional independence, quality of life, age, and lesion level in myelomeningocele patients, and investigate the influence of hydrocephalus on thes...

[Purpose] This study investigated the relationship between activity limitation and participation restriction in school-aged children with cerebral palsy. [Subjects and Methods] Data were collected from 109 children with cerebral palsy aged 6-12 years. Activity limitations were assessed by using functional classification systems including the Korean-Gross Motor Function Classification System, th...

INTRODUCTION The prevalence of oropharyngeal dysphagia (OPD) in children with cerebral palsy (CP) is estimated to be between 19% and 99%. OPD can impact on children's growth, nutrition and overall health. Despite the growing recognition of the extent and significance of health issues relating to OPD in children with CP, lack of knowledge of its profile in this subpopulation remains. This study ...

This study examined the acquisition and long-term retention of a gross motor skill, namely, tossing, in 23 moderately to severely demented Alzheimer's disease (AD) patients and 22 health older adults. To identify optimal learning strategies, subjects received 10 weeks of training under either constant or variable practice conditions. Accuracy at the tossing task was assessed immediately, one we...