Monozygous twin sisters developed ulcerative colitis within 7 years of each other. Both had distal colitis confirmed by histology and radiology. Their maternal grandmother subsequently developed the disease. The long interval between the onset of the disease in the twins suggests a role for environmental factors in addition to genetic influences. Although about five hundred sets of twins with u...

Abstract The aim of the current study was to examine mentoring relationship with closest grandparent, considering perceived grandparent’s perspective taking, and identity processes among Polish emerging adult grandchildren. A total 424 adults (41.3% male) aged 18–25 completed self-assessment measures. structural equation modeling analysis revealed positive associations between perception relati...

We extended our research on the architecture, growth and age of trees belonging to the genus Adansonia, by starting to investigate large individuals of the most widespread Malagasy species. Our research also intends to identify the oldest baobabs of Madagascar. Here we present results of the radiocarbon investigation of the two most representative Adansonia rubrostipa (fony baobab) specimens, w...

BACKGROUND This article reports on formative research into the context and practice of handwashing with soap by new mothers, which can substantially impact child morbidity and mortality. New mothers are an important target group for handwashing interventions: they are considered particularly susceptible to behaviour change and their actions can directly affect a child's health. METHODS Twenty...

OBJECTIVE The objective of this work was to determine the prevalence, sociodemographic characteristics, and service utilization patterns of African American grandparents raising grandchildren compared with noncaregiving peers. METHODS Data were obtained from the Census 2000 Supplementary Survey/American Community Survey, a nationally representative survey of 890,000 households. Analysis was b...

Sporadic and familial nonautoimmune hyperthyroidism are very rarely occurring diseases. Within the last years constitutively activating TSH receptor mutations were identified as one possible pathomechanism. Except for S281N in the extracellular N-terminal domain, all other germline mutations are located in the transmembrane domains 2, 3, 5, 6, and 7 of the TSH receptor, whereas no mutation was ...

Down syndrome (DS), trisomy 21, is the most common chromosomal syndrome that affects one in 600800 live births. The advanced maternal age is the only well known risk factor to cause DS. Our study revealed that many young mothers produced DS children than advanced age mothers in India. A total of 150 suspected DS cases were investigated cytogenetically. Randomly selected 200 healthy families in ...

OBJECTIVE To examine sporadic cases of primary pulmonary hypertension of coancestry. DESIGN An epidemiologic study of families of patients with primary pulmonary hypertension. SETTING A university-affiliated referral population. PARTICIPANTS Family members of 13 patients with primary pulmonary hypertension. MEASUREMENTS Family pedigrees involving grandparents, parents, siblings, and chi...