There is an epidemic of obesity, type 2 diabetes, metabolic syndrome and associated conditions. Patients with these conditions often have markers of increased inflammation. Many researchers have published that nutrition overload caused the epidemic of obesity and the associated inflammation which leads to type 2 diabetes and metabolic syndrome. A contrasting view has provided extensive evidence...

Several distinct congenital disorders can lead to tissue-iron overload with anemia. Repeated blood transfusions are one of the major causes of iron overload in several of these disorders, including β-thalassemia major, which is characterized by a defective β-globin gene. In this state, hyperabsorption of iron is also observed and can significantly contribute to iron overload. In β-thalassemia i...

The recent technological advancement has proved to be tremendously helpful for medical consultants. However, this advancement has also generated an enormous volume and variety of data, with a high velocity causing an information load for the medical consultants. Information overload can be defined as a difficulty a person can have in comprehending issue and making judgments that are caused by t...

This paper describes a runtime scheduling method for a mix of off-line scheduled and value based dynamic tasks with a focus on overload situations. We present a formulation of overload handling as a general binary optimisation problem and give an algorithm for solving it. Our method is based on slot shifting [4] to provide for the integration of offline and online scheduling. Dynamic tasks are ...

This study's purpose was to examine whether functional overload with nandrolone decanoate (ND) administration increased muscle mass and steroid receptor concentration in aged rat soleus (Sol) and plantaris (Plan) muscle. ND (6 mg/kg body wt) was administered once a week for 4 wk, whereas control rats received sesame seed oil injections. Functional overload of the hindlimb Sol and Plan was induc...

Petrak, Jiri, Denisa Myslivcova, Petr Man, Radek Cmejla, Jana Cmejlova, and Daniel Vyoral. Proteomic analysis of iron overload in human hepatoma cells. Am J Physiol Gastrointest Liver Physiol 290:G1059–G1066, 2006. First published January 12, 2006; doi:10.1152/ajpgi.00469.2005.—Iron-mediated organ damage is common in patients with iron overload diseases, namely, hereditary hemochromatosis. Mass...

The mechanisms of stress-assisted grain growth are explored using molecular dynamics simulations of nanoindentation in nanocrystalline Ni and Ni-1 at.% P as a function of grain size and deformation temperature. Grain coalescence is primarily confined to the high stress region beneath the simulated indentation zone in nanocrystalline Ni with a grain size of 3 nm. Grain orientation and atomic dis...

Genetic improvements have significantly contributed to wheat production. Five wheat cultivars-widely grown in north China in the 1950s, 1990s, or 2010s-were grown in field experiments conducted in the 2014-2015 and 2015-2016 growing seasons. This study evaluated the genetic progress in wheat grain yield and its related traits in north China and explored how breeding and selection have influence...

Although many animal studies indicate insulin has cardioprotective effects, clinical studies suggest a link between insulin resistance (hyperinsulinemia) and heart failure (HF). Here we have demonstrated that excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents. Chronic pressure overload induced hepatic insulin resistance and plasma insuli...

Last year’s trend to migrate circuit-switched voice networks to packet switched Internet Protocol (IP) based networks has favored wide deployment of Session Initiation Protocol (SIP) based systems and networks. As a reaction to large-scale SIP deployment experiences in the field and the need to implement high availability and reliability within these new networks, the focus of SIP extension sta...