An efficient immobilization of Glucose oxidase (GOx) on an appropriate substrate is one the main challenges developing fuel cells that allow energy to be obtained from renewable substrates such as carbohydrates in physiological environments. The research importance biofuel relies their experimental robustness and high compatibility with biological organisms tissues or bloodstream aim obtaining ...

Targeted delivery of drugs to vascular endothelium promises more effective and specific therapies in many disease conditions, including acute lung injury (ALI). This study evaluates the therapeutic effect of drug targeting to PECAM (platelet/endothelial cell adhesion molecule-1) in vivo in the context of pulmonary oxidative stress. Endothelial injury by reactive oxygen species (e.g., H2O2) is i...

BACKGROUND So far, no study has explored the effects of sevoflurane, propofol, and Intralipid on metabolic flux rates of fatty acid oxidation (FOX) and glucose oxidation (GOX) in hearts exposed to ischaemia-reperfusion. METHODS Isolated paced working rat hearts were exposed to 20 min of ischaemia and 30 min of reperfusion. Peri-ischaemic sevoflurane (2 vol%) and propofol (100 µM) in the formu...

Back Cover: In article number 2100121, Suchetan Pal and co-workers develop a family of multi-responsive polymer hydrogels crosslinked with bis boronic acid molecules. Hydrogels tetrahydroxydiboron show glucoseresponsive degradation in the presence glucose oxidase (GOX) enzyme. Furthermore, insulin releases under high conditions physiological milieu.

We tested two genes together in hybrid poplars (genus Populus), CP4 and GOX, for imparting tolerance to glyphosate (the active ingredient in Roundup® herbicide). Using Agrobacterium-based transformation, 80 independent transgenic lines (i.e., products of asexual gene transfer) were produced in a variety of hybrid poplar clones (40 lines in Populus trichocarpa Torr. & Gray × Populus deltoides Ba...

Diabetic ulcers induced by multidrug-resistant (MDR) bacteria have severely endangered diabetic populations. These are very challenging to treat because the local high glucose concentration can both promote bacterial growth and limit immune system's bactericidal action. Herein, a oxidase-peroxidase (GOx-POD) dual-enzyme mimetic (DEM) bionanocatalyst, [email protected] is synthesized simultaneou...

Climate change is modifying the composition of grapes, increasing sugar and pH levels, which produces unbalanced wines with high alcohol degree, low acidity poor aromatic notes. In this study, glucose oxidase (GOX) catalase (CAT) were applied in white must content (>3.8) to simultaneously decrease concentration pH. The effect enzyme treatment on volatile wine was investigated. A 0.17 mkat/L for...

Compartmentalization is a ubiquitous feature of life, with membrane interface that regulates molecular transport and exhibits bioactivities. An artificial enzyme-integrated cascade system can mimic such interactive properties across different length scales for in vitro application. Here, it shown reticulated nanoporous framework nano-caged enzymes presents the first modular macroscale platform ...