The Bristol Bay region of southwestern Alaska is sparsely inhabited, but richly endowed in resources that could support a major tourism industry. Despite an abundance of natural and cultural attractions and a clear need for economic diversification, the tourism industry is still largely undeveloped. Several factors account for this unfulfilled opportunity, including high travel costs, lack of v...

Precisely measuring θ13 is one of the highest priority in neutrino oscillation study. Reactor experiments can cleanly determine θ13. Past reactor neutrino experiments are reviewed and status of next precision θ13 experiments are presented. Daya Bay is designed to measure sin 2θ13 to better than 0.01 and Double Chooz and RENO are designed to measure it to 0.02-0.03. All are heading to full opera...

Science consists of both a body of knowledge and a process by which the knowledge is produced. Historically, these two aspects were often assessed separately (i.e., test items on knowledge and test items on skills) and taught relatively separately (e.g., with an introduction section on skills or via isolated projects or labs). The last decade has been marked by a substantial shift to an integra...

Kowloon Bay Integrated Treatment Centre, 9/F Kowloon Bay Health Centre, 9 Kai Yan Street, Kowloon Bay, Kowloon, Hong Kong This is a case report of a 20-month-old boy who presented with multiple asymptomatic nodules on the left pretibial area. He had no history of diabetes or other systemic diseases. Family history was unremarkable. Skin biopsy showed palisading granuloma in deep dermis and subc...

James, Hudson and Ungava bays are summering areas for stocks of beluga whales (Delphinapterus leucas) (Sergeant and Brodie, 1975; Finley et al., 1982; Smith and Hammill, 1986; Richard et al., 1990). There are several apparently separate summer groups, which include a summer group of ~23,000 individuals in western Hudson Bay, a group of 1500 individuals in the eastern Hudson Bay arc, and a few i...

The goal of this study was to compare responses to a calcium promoter, BAY y 5959, and dobutamine (Dob) in heart failure (HF). Dogs ( n = 9) were chronically instrumented and studied in the conscious state before and after pacing-induced HF. In the control state, BAY y 5959 (20 μg ⋅ kg-1 ⋅ min-1) increased the first derivative of left ventricular (LV) pressure (dP/d t) by 83 ± 8% and mean arter...

Nasu K, Nishida M, Ueda T, Yuge A, Takai N, Narahara H. Application of the nuclear factorB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study. Am J Physiol Endocrinol Metab 293: E16–E23, 2007. First published August 8, 2006; doi:10.1152/ajpendo.00135.2006.—Most of the current medical treatments for endometriosis aim to downregulate estrogen activity. However, a high rec...

[1] During spring and summer time, coastal upwelling influences circulation and ecosystem dynamics of the Monterey Bay, California, which is recognized as a National Marine Sanctuary. Observations of physical, bio‐optical properties (including bioluminescence) together with results from dynamical biochemical and bioluminescence models are used to interpret the development of the upwelling event...

Guanabara Bay is the second largest bay in the coast of Brazil, with an area of 384 km(2). In its surroundings live circa 16 million inhabitants, out of which 6 million live in Rio de Janeiro city, one of the largest cities of the country, and the host of the 2016 Olympic Games. Anthropogenic interference in Guanabara Bay area started early in the XVI century, but environmental impacts escalate...

The aim of this study was to establish the involvement of acetylcholine (Ach) and calcium ions in modulating contractions induced by Bay K8644 (an agonist of calcium channels located in the cell membrane) and KCl (at depolarizing concentrations), and also to examine the importance of the vascular endothelium in the activity of Bay K8644. The study was performed on perfused Wistar rat tail arter...