paclitaxel is a highly effective anticancer agent. it is active against a broad range of cancers that are generally considered refractory to conventional chemotherapy. paclitaxel induces a peripheral neuropathy (pn) that is characterized by sensory symptoms such as numbness and paresthesia in a glove and stocking distribution. pn may be severe and dose limiting at initial doses above 275 mg/m2....

A 12 year old girl referred for chromosome analysis because of short stature was found to have karyotype mos 45,X/46,X,+mar. The marker chromosome was observed in 58% of her blood lymphocytes. It was a small, pale staining, spherical fragment with GTL banding and showed faint differentiation along its length with CBG banding. DNA analysis using Y specific probes showed the absence of the testic...

introduction: delivering maximum dose to tumor and minimum dose to normal tissues is the most important goal in radiotherapy. according to icru, the maximum acceptable uncertainty in the delivered dose compared to the prescribed dose should be lower than 5%, and this is because of the relationship between absorbed dose, tumor control and normal tissue damage. absorbed dose accuracy is investiga...

since sturgeons have no external sexual dimorphism and there are no external markers to determine sex, internal examination of the gonads should be used to sex identification. the present study describes the biopsy method and histological observations of the gonads of great sturgeon (huso huso) in both sexes at different age classes. sex and maturity stages of 226 great sturgeons were identifie...

Background: Medical X-rays are the largest man-made source of public exposure to ionizing radiation. While the benefits of Computed Tomography (CT) are well known in accurate diagnosis, those benefits are not risk-free. CT is a device with higher patient dose in comparison with other conventional radiation procedures. Objective: This study is aimed at evaluating radiation dose to patients from ...