In this paper, I treat the subject concerned with the theory of Suppositio in the Mexican golden age, as exposed by Alonso de la Veracruz [Ver82, ReBe85] and Tomás de Mercado [ReBe85]. According to this tradition, supposition is a property of terms occurring in propositions and are such that are verifiable of what they signify. On the one hand, there is a taxonomy in which suppositions are clas...

In 1667, Cosimo de Medici, heir to the Grand Duchy of Tuscany, embarked on a grand tour of Europe, mostly at his father’s urging, in order to escape his unhappy marriage to a cousin of French king Louis XIV.1 Prince Cosimo’s travels took him to, among other places, the province of Holland in the Dutch Republic, where he famously visited the aging painter Rembrandt van Rijn in Amsterdam.2 Religi...

Once upon a time, immunology was a black box, inflammatory and autoimmune diseases were a mystery, and relatively blunt tools were used to treat these diseases. In the last 40 years, advances in molecular biology, DNA recombination technology, and genome sequencing allowed immunologists to open the box. As the complexity and diversity of the immune response are unveiled, targeted cellular and m...

The notion of Ubiquitous (or Pervasive) Computing was first eloquently described by Mark Weiser at Xerox PARC in the early 1990’s. He proposed a vision in which the personal computing model would evolve from one person using one computer, to many (perhaps hundreds) of computers per person; and that computing would become wirelessly embedded in the world around us, tacitly supporting our work pr...

The 2012 Nobel Prize in Medicine or Physiology recognizes the architects of two of the great paradigm-shifting discoveries of the last half-century of biology. In experiments performed nearly 50 years apart, Gurdon and Yamanaka made feasible the reawakening of pluripotency inherent in all cells and challenged forever our notions of cellular identity.