Metal nanoparticles (NPs) scatter and absorb light in precise, designable ways, making them agile candidates for a variety of biomedical applications. When NPs are introduced to a physiological environment and interact with cells, their physicochemical properties can change as proteins adsorb on their surface and they agglomerate within intracellular endosomal vesicles. Since the plasmonic prop...

BACKGROUND Diseases such as tuberculosis (TB) have always had a large impact on human health. Bacillus Calmette-Guérin (BCG) is used as a surrogate for TB during the development of anti-TB drugs. Nanoparticles (NPs) have attracted great interest in drug development. The purpose of this study was to examine the potential of NPs as anti-TB compounds by studying the interacting mechanisms between ...

DOI: 10.1002/admi.201400187 The propensity of Au ions to self-assemble and undergo rapid reduction into colloids and NPs, however, poses distinct barriers for utilizing conventional gold chemistry for creating structurally-defi ned, organized wire structures and thin fi lms. Patterned Au structures have been produced through chemical derivation of gold colloids surfaces [ 14 ] and/or the substr...

Water-soluble gold nanoparticles (Au NPs) stabilized by a nitrogen-rich PEG-tagged substrate have been prepared by reduction of HAuCl4 with NaBH4 in water at room temperature. The morphology and size of the nanoparticles can be controlled by simply varying the gold/stabilizer ratio. The nanoparticles have been fully characterized by TEM, HRTEM, ED, EDS, UV-vis, p-XRD and elemental analysis. The...

A comparative study of the surface-enhanced Raman scattering (SERS) effect of the spherical gold nanoparticles (NPs) and highly uniform and oriented gold nanotriangles (NTs), anchored on indium tin oxide (ITO) coated conducting glass surfaces is reported. Contact and non-contact mode atomic force microscopic (AFM) analyses confirmed that all the triangles observed are equilateral and uniformly ...

Thermo- and electro-optical properties of a photonic liquid crystal fiber (PLCF) enhanced by the use of dopants have been investigated. A 6CHBT nematic liquid crystal was doped with four different concentrations of gold nanoparticles (NPs), 0.1, 0.3, 0.5 and 1.0 wt %, for direct comparison of the influence of the dopant on the properties of the PLCF. The thermo-optical effects of the liquid cry...

Metallic nanostructures were prepared through the alternate immersion of derivatized glass slides in solutions of gold nanoparticles (NPs) and a propanedithiol linker molecule. Nanostructures consisting of 1-17 depositions of gold NPs were synthesized, and these substrates were characterized using UV-vis spectroscopy and atomic force microscopy. Subsequently, the surface-enhanced Raman scatteri...

To increase the flexibility of surface-attached bio-relevant ligands on gold nanoparticle (NP), hetero-bifunctional poly(ethylene glycol) (PEG), was synthesized having two different functional groups on both the terminals. Coumarin was conjugated to the gold NP through the PEG spacer. The results of cellular cytotoxicity and fluorescence microscopy showed that these NPs were non-toxic and could...

Simultaneous quantification of drug isomers, methylxanthines (MeX), by SERS via self-assembly gold nanoparticles (Au NPs) mediated cucurbit[ n ]urils (CBs).

The electro-mechanical sensing properties of freestanding monolayered membranes of dodecanethiol coated 7 nm gold nanoparticles (NPs) are investigated using AFM force spectroscopy and conductive AFM simultaneously. The electrical resistance of the NP membranes increases sensitively with the point-load force applied in the center of the membranes using an AFM tip. Numerical simulations of electr...