The repeated evolution of herbicide resistance in weeds is an ongoing problem in agricultural regions across the world, and presents a unique system in which to study the origins and spread of adaptive traits across heterogeneous landscapes. Lolium perenne ssp. multiflorum (Lam.) (Italian ryegrass) is a widespread grass weed of agricultural crops that has repeatedly evolved resistance to herbic...

As glyphosate is a broad spectrum herbicide extensively used in agriculture worldwide, identification of new aroA genes with high level of glyphosate tolerance is essential for the development and breeding of transgenic glyphosate-tolerant crops. In this study, an aroA gene was cloned from a Janibacter sp. strain isolated from marine sediment (designated as aroAJ. sp). The purified aroAJ. sp en...

Many neurological diseases, including autism, depression, dementia, anxiety disorder and Parkinson’s disease, are associated with abnormal sleep patterns, which are directly linked to pineal gland dysfunction. The pineal gland is highly susceptible to environmental toxicants. Two pervasive substances in modern industrialized nations are aluminum and glyphosate, the active ingredient in the herb...

To assess human health risk from environmental chemicals, we have studied the effect on cell cycle regulation of the widely used glyphosate-containing pesticide Roundup. As a model system we have used sea urchin embryonic first divisions following fertilization, which are appropriate for the study of universal cell cycle regulation without interference with transcription. We show that 0.8% Roun...

Glyphosate [N-phosphonomethyl]glycine is a systematic, non-selective, organophosphorus herbicide used worldwide in agriculture and industrial zones. Following its application, residues of glyphosate can threaten soil or aquatic organisms in adjacent water. In this study, we followed the degradation, stabilization, remobilization and leaching of C-glyphosate in three agricultural soils in labora...

Glyphosate is the main nonselective, systemic herbicide used against a wide range of weeds. Its worldwide use has expanded because of extensive use of certain agricultural practices such as no-till cropping, and widespread application of glyphosate-resistant genetically modified crops. Glyphosate has a reputation of being nontoxic to animals and rapidly inactivated in soils. However, recent evi...

Glyphosate (N-phosphonomethyl glycine) is one of the most widely used pesticide around the world. It is very well known that glyphosate compound rapidly degrades into aminomethylphosphonic acid (AMPA) metabolite (Fig. 1). Glyphosate is a herbicide with a broad spectrum of activity, very effective even on plant roots with little harmful effects on mammals. Its high efficacy, low toxicity and aff...

The adsorption, desorption, degradation, and mineralization of C-glyphosate [-(phosphonomethyl)glycine] were examined in Catlin (a fine-silty, mixed, superactive, mesic Oxyaquic Argiudoll), Flanagan (a fine, smectitic, mesic Aquic Argiudoll), and Drummer (a fine-silty, mixed, superactive, mesic Typic Endoaquoll) soils under oxic and anoxic soil conditions. With the exception of the Drummer soil...

In recent years, pesticides were used heavily in Palestine, which led to the contamination of soil and water and causing many diseases. Many studies focused on the impact of pollutants such as pesticides and oil on soil, humans, animals, plants and the environment in general. Using column study the amount of glyphosate in soil decreases with increasing depth of soil, where it is for 0-30cm(11pp...

CONTEXT The case fatality from acute poisoning with glyphosate-containing herbicides is approximately 7.7% from the available studies but these have major limitations. Large prospective studies of patients with self-poisoning from known formulations who present to primary or secondary hospitals are needed to better describe the outcome from acute poisoning with glyphosate-containing herbicides....