BACKGROUND Endothelial progenitor cells (EPCs) play an important role in vascular repair and a decrease in the number of EPCs is observed in type 2 diabetes. However, there is no report on the change of EPCs after glycemic control. This study therefore aimed to investigate the EPC number and function in patients with good and poor glycemic control. METHODS The number of EPCs was studied using...

The selection of a glycemic goal in a person with diabetes is a compromise between the documented upside of glycemic control-the partial prevention or delay of microvascular complications-and the documented downside of glycemic control-the recurrent morbidity and potential mortality of iatrogenic hypoglycemia. The latter is not an issue if glycemic control is accomplished with drugs that do not...

BACKGROUND Major macronutrients for energy intake vary among countries and cultures. Carbohydrates, including rice, are the major component of daily energy intake in Korea. The aim of this study was to examine the association of daily energy intake or each proportion of macronutrients, especially carbohydrates, with glycemic control in diabetic Koreans. METHODS A total of 334 individuals with...

BACKGROUND Type 2 diabetes (T2DM) patients, including those in good glycemic control, have an increased risk of cardiovascular disease (CVD). Maintaining good glycemic control may reduce long-term CVD risk. However, other risk factors such as elevated vascular sympathetic tone and/or endothelial dysfunction may be stronger potentiators of CVD. This study evaluated the impact of bromocriptine-QR...

OBJECTIVE We sought to measure the prevalence of inadequate glycemic control in prevalent hemodialysis patients with diabetes and to examine independent predictors of inadequate glycemic control in these patients. RESEARCH DESIGN AND METHODS This is a cross-sectional study of prevalent hemodialysis patients with diabetes in southeastern Ontario (n = 100). Data were collected by chart review a...

This is the first of three articles dealing with the International Diabetes Federation meeting, which was held in Paris, 24–29 August 2003. Michael Stumvoll (Tübigen, Germany) gave the Minkowski lecture, discussing aspects of the control of glycemia, illustrating the “hyperbolic law of glucose control,” depicting the inverse relationship between insulin secretion and insulin sensitivity. If one...

Heart failure (HF) is a common and often neglected complication of type 2 diabetes mellitus (T2DM). The association is caused by the role of T2DM as a risk factor for coronary artery disease, its comorbidities (eg, hypertension) that themselves cause HF, and the direct effects of T2DM on the myocardium. This diabetic cardiomyopathy arises from multiple causes, including disease of the interstit...