BACKGROUND Globus pharyngeus is a sensation of a lump or foreign body in the throat, sometimes associated with thyroid diseases and surgery. Previous studies investigated this condition with contradictory results, mainly because not standardized instruments of measure were used. The aim of this study was to evaluate the prevalence and severity of globus pattern symptoms in a population of patie...

This paper suggests and develops a new methodology of estimation for multivariable reachability region plasma separatrix shape on the divertor phase discharge in D-shaped tokamaks. The is applied to spherical Globus-M/M2 tokamak, including controllability vertical unstable position basis experimental data. An assessment important design tokamak poloidal field coils synthesis magnetic control sy...

background: carbon monoxide (co) poisoning may lead to hypoxic/anoxic injury and eventually ischemic encephalopathy. magnetic resonance imaging (mri) has a well-recognized role in assessment of the severity of brain damage caused by co poisoning. in this study, we aimed to present and analyze the structural abnormalities in the brain mri and especially in diffusion weighted mri (dwi) images in ...

The endomorphins are recently discovered endogenous agonists for the mu-opioid receptor (Zadina et al., 1997). Endomorphins produce analgesia; however, their role in other brain functions has not been elucidated. We have investigated the behavioral effects of endomorphin-1 in the globus pallidus, a brain region that is rich in mu-opioid receptors and involved in motor control. Bilateral adminis...

The undecapeptide substance P has been demonstrated to modulate neuronal activity in a number of brain regions by acting on neurokinin-1 receptors. Anatomical studies revealed a moderate level of neurokinin-1 receptor in rat globus pallidus. To determine the electrophysiological effects of neurokinin-1 receptor activation in globus pallidus, whole-cell patch-clamp recordings were performed in t...

BACKGROUND Patients with Parkinson disease (PD) may be akinetic/rigid, be tremor dominant, or have comparable severity of these motor symptoms (classic). The pathophysiologic basis of different PD phenotypes is unknown. This study assessed pallidal and striatal dopamine level patterns in different motor subgroups of PD and normal control brains. METHODS Globus pallidus and striatum dopamine (...