BACKGROUND Studies on obesity and glycemic index (GI) or glycemic load (GL) have had inconsistent results, perhaps in part because of underreporting or to heterogeneous dietary patterns across food cultures. OBJECTIVES We examined associations between body mass index (BMI) and GI or GL in a Mediterranean population, accounting for underreporting. We also constructed dietary factors related to...

Antibodies readily neutralize acute, epidemic viruses, but are less effective against more indolent pathogens such as herpesviruses. Murid herpesvirus 4 (MuHV-4) provides an accessible model for tracking the fate of antibody-exposed gammaherpesvirus virions. Glycoprotein L (gL) plays a central role in MuHV-4 entry: it allows gH to bind heparan sulfate and regulates fusion-associated conformatio...

Galiellalactone (GL) is a fungal metabolite that presents antitumor activities on prostate cancer in vitro and in vivo. In this study we show that GL induced cell cycle arrest in G2/M phase, caspase-dependent apoptosis and also affected the microtubule organization and migration ability in DU145 cells. GL did not induce double strand DNA break but activated the ATR and ATM-mediated DNA damage r...

Background: Acne is a chronic inflammatory skin disease and a cosmetic problem with considerable emotional and psychological side effects and symptoms, such as pain and pruritus. Some controversies exist concerning the involvement of dietary factors, including glycemic load (GL), in the pathogenesis of acne. Accordingly, we aimed to determine the role of GL and anthropometric m...

Considering quantales as generalised noncommutative spaces, we address as an example a quantale Pen based on the Penrose tilings of the plane. We study in general the representations of involutive quantales on those of binary relations, and show that in the case of Pen the algebraically irreducible representations provide a complete classification of the set of Penrose tilings from which its re...

The concepts of fuzzy source and fuzzy successor operators for an L-fuzzy automaton (L is a latticeordered monoid) are introduced, which turn out to be L-fuzzy closure operators. When L is a quantale, these operators introduce L-fuzzy topologies. These observations are then used to give topological characterization of the separatedness and connectedness properties of an L-fuzzy automaton. c ©20...

Getting lost (GL) is a serious problem for people living with Alzheimer's disease (PwAD), causing psychological distress in both PwAD and caregivers, and increasing the odds of being institutionalized. It is thus important to identify risk factors for the GL events in PwAD. Between April 2009 and March 2012, we invited 185 community-dwelling PwAD and their caregivers to participate in this stud...

This is an essay on potential theory for geometric plurisubharmonic functions. It begins with a given closed subset Gl of the Grassmann bundle G(p, TX) of tangent p-planes to a riemannian manifold X . This determines a nonlinear partial differential equation which is convex but never uniformly elliptic (p < dimX). A surprising number of results in complex analysis carry over to this more genera...

Glycolate(GL)-based polyesters were for the first time produced in the recombinant Escherichia coli fatty acid β-oxidation pathway reinforcing mutant LS5218, using extracellularly added GL as a monomer precursor. Cells expressing a Ser325Thr/Gln481Lys mutant of polyhydroxyalkanoate synthase (PhaC1STQK) from Pseudomonas sp. 61-3, propionyl-CoA transferase from Megasphaera elsdenii and enoyl-CoA ...

We propose algorithms to get representatives and the images of the moment map of conormal bundles of GL(p,C)×GL(q,C)-orbits in the flag variety of GL(p+q,C), and GL(p+q,C)-orbits and Sp(p,C)×Sp(q,C)-orbits in the flag variety of Sp(p+ q,C) and their signed Young diagrams.