Aim: A common side effect of calcium channel blockers, which are frequently used in the treatment patients with hypertension and cardiovascular problems, is that they can cause overgrowth gingiva. Gingival overgrowths should be treated because create inaccessible areas, making oral hygiene practices difficult due to increased plaque retention. In this case series, clinical properties gingival d...

Objectives: Gingival enlargement as an adverse effects of drugs has been found to be long associated with the use of anticonvulsants; phenytoin, anti-hypertensives; calcium channel blockers and immunosuppressants; cyclosporine. Nifedepine was found to cause gingival overgrowth with an incidence ranging from 15-85%. However, Amlodepine a relatively newer agent of the same group which is being ro...

The peripheral ossifying fibroma, a benign gingival overgrowth, occurs mainly in the anterior portion of the maxilla in young adults. The size of the lesion is usually less than 1.5 cm. We report a case of peripheral ossifying fibroma overlying the mandibular alveolar ridge of a 55-year-old female. MR scans showed a large exophytic soft tissue mass overlying mandibular alveolar ridge. The tumor...

Endothlin-1 (ET-1) is a 21 amino acid peptide and is a potent vasoconstrictor produced by endothelial cells. It plays a role in the development of diseases such as hypertension and atherosclerosis. Reports have suggested the identification of ET-1 in chronic periodontitis and gingival overgrowth. Thus, there is a need to appraise the role of ET-1 in periodontal disease. Further research is need...

Background: Gingival overgrowth may be idiopathic or secondary. Drug Induced Overgrowth (DIGO) occurs within 3 months of treatment and is more prevalent in younger age group with predilection for the anterior gingival tissue usually not associated attachment loss tooth mobility unless there an existing periodontal disease. Methodology: 170 hypertensive patients were recruited study; 85 calcium ...