Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. Its histogenesis remains unclear. It is characterized by a proliferation of mononuclear stromal ...

Giant-cell tumor of bone occurred in the distal end of the ulna is extremely uncommon. A 23-year-old male had a giant-cell tumor occurred in the distal end of the ulna. After wide resection of the distal segment of the ulna including giant-cell tumor, ulnar components of the wrist joint were reconstructed with modified Sauvé-Kapandji procedure using the iliac bone graft, preserving the triangul...

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

Background: Schwannoma is a peripheral nerve sheath tumor originating from schwann cells. It is the most common neurogenic tumor of the posterior mediastinum. Pleural effusion is a rare presentation of benign schwannoma and it is mainly related to malignant tumors. Histologically, schwannoma as well as solitary fibrous tumor should be considered as a differential diagnosis of spindle cell lesio...

OBJECTIVES To identify incidence and utility of histopathology in wrist ganglions.  METHODS A retrospective study of 112  patients operated for wrist swellings between January 2009 and March 2014 at Aga Khan University Hospital, Karachi, Pakistan, was conducted. Medical records were reviewed for demographics, history, location and associated symptoms, provisional diagnosis and operative detai...

The purpose of this study was to clarify clinical and radiographic features of bone changes associated with soft-tissue tumors of the hand. We reviewed clinical records and radiographs of 115 patients who had undergone operations for soft-tissue tumors or tumorous conditions of the hand. Bone changes were detected in the radiographs of 21 of the 115 patients. Giant cell tumor of tendon sheath w...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 there are a few case series of giant cell tumor (gct) in the spine and sacrum. gct in the thoracic vertebrae is even more exceptional in the medical literature. in this article we report a gct in a 25-year-old male who presented with progressive back pain and dyspnea. on contrast-enhanced multidetector computer tomography,...

The case was a male patient, 65 years old, with no relevant medical history, who was consulted due to painless swelling on the dorsal side of the fifth finger of the left hand which had lasted for 4 years, with no history of trauma. Physical examination confirmed the tumor, elastic on palpation, with preserved finger mobility (Fig. 1) Simple X-rays showed a soft tissue tumor (Fig. 2); the ultra...