OBJECTIVE To identify patients with gestational diabetes mellitus (GDM) who will need antenatal insulin treatment (AIT) by using a risk-prediction tool based on maternal clinical and biochemical characteristics at diagnosis. RESEARCH DESIGN AND METHODS Data from 3,009 women attending the Royal Prince Alfred Hospital GDM Clinic, Australia, between 1995 and 2010 were studied. A risk engine was ...

AIMS/INTRODUCTION The aims of the present study were to investigate the performance of a novel sandwich enzyme-linked immunosorbent assay (ELISA) for measuring glucagon (1-29) with monoclonal antibodies against both the C- and N-terminal regions of glucagon (1-29), and to analyze the differences in plasma levels and responses of glucagon (1-29) to oral glucose loading in normal glucose toleranc...

Background: The efficacy of various screening variables in detection of diabetes mellitus (DM) is unclear. Objective: To determine the efficacy of various diagnostic tests for type 2 DM. Methods: 1021 inhabitants of Hakimieh district of Tehran aged between 30 and 75 years were studied.  Known cases of diabetes and those with factors influencing glucose tolerance test were excluded.  Age, sex, f...

We do not agree with their statement, “In high risk populations such as Asians, the World Health Organization (WHO) advocates screening during the first trimester to detect previously undiagnosed diabetes and a formal oral glucose tolerance test between 24 and 28 weeks of gestation to diagnose gestational diabetes mellitus”. One of the principal criteria for screening as defined by the WHO is t...

In this study, morphometric measures of placental terminal villi and villous vessels were compared in overt, as well as gestational diabetes mellitus, and mild hyperglycemia diagnosed by oral 100 g glucose tolerance test (100 g-OGTT) and glucose profile (GP). At delivery (gestational age> or =34 weeks) a total of 207 placentas were assigned to a control group (n=56) or to one of three groups co...

Objective: To determine the frequency of gestational diabetes mellitus (GDM) among pregnant females. Study Design: Cross-sectional study. Place and Duration: Department Gynecology Obstetrics, department Pathology, Dow University health sciences, From February 2021 to January 2022. Methodology: Five hundred ladies with age between 24-28 weeks any parity were included. These women challenged 75 g...

BACKGROUND/AIMS The aim was to compare the insulin sensitivity and secretion index of pregnant Korean women with normal glucose tolerance (NGT), gestational impaired glucose tolerance (GIGT; only one abnormal value according to the Carpenter and Coustan criteria), and gestational diabetes mellitus (GDM). METHODS A cross-sectional study was performed with 1,163 pregnant women with positive (1-...