Case-based design (CBD) overcomes certain dficulties associated with traditional knowledge-based design systems. When novel designs are created by adapting cases, design integrity can be maintained through careful formulation of adaptation procedures. We describe a prototype design system called case adaptation by dimensionality reasoning (CADRE). Geometrical information is treated through simu...

Numerical analysis of pulsatile blood flow in healthy, stenosed, and stented carotid arteries is performed with the aim of identifying hemodynamic factors in the initiation, growth, and the potential of leading to severe occlusions of a diseased artery. The Immersed Finite Element Method is adopted for this study to conveniently incorporate various geometrical shapes of arteries without remeshi...

Despite efforts for over 25 years, de novo protein design has not succeeded in achieving the TIM-barrel fold. Here we describe the computational design of four-fold symmetrical (β/α)8 barrels guided by geometrical and chemical principles. Experimental characterization of 33 designs revealed the importance of side chain-backbone hydrogen bonds for defining the strand register between repeat unit...

Motivated by recent interest in group-symmetry in the area of semidefinite programming, we propose a numerical method for finding a finest simultaneous block-diagonalization of a finite number of symmetric matrices, or equivalently the irreducible decomposition of the matrix ∗-algebra generated by symmetric matrices. The method does not require any algebraic structure to be known in advance, wh...

All-dielectric "magnetic light" nanophotonics based on high refractive index nanoparticles allows controlling magnetic component of light at nanoscale without having high dissipative losses. The artificial magnetic optical response of such nanoparticles originates from circular displacement currents excited inside those structures and strongly depends on geometry and dispersion of optical mater...

Origami is the art and science of making various shapes by simply folding a sheet of paper. When origami is studied as a geometrical problem, it is often assumed that the origami is folded flat. This flat foldability is an important property when we consider applying the techniques of origami to increase the portability and storage space of industrial products. We propose a method to generate n...

The wide varieties of Indonesian textiles could reflect the varsity that has been living with the diversity of Indonesian ethnic groups. Meme as an evolutionary modeling technique promises some conjectures to capture the innovative process of the cultural objects production in the particular collective patterns acquainted can be regarded as fitness in the large evolutionary landscape of cultura...

INTRODUCTION HIP FRACTURES, which represent a severe health problem for the elderly, typically result in sideways falls with a direct impact to the hip (Kannus et al. 1999). One possibility to prevent hip fractures is the use of hip protectors. At present, mainly two types of products, namely energy-absorbing soft pads and energy-shunting hard shells are used to protect the hip from impact load...

A novel methodology has been used to design an evaporator coil of a refrigerant. The methodology used is through a complete Computer Aided Design /Computer Aided Engineering approach, by means of a Computational Fluid Dynamic/Finite Element Analysis model which is executed many times for the thermal-fluid exploration of several designs' configuration by an commercial optimizer. Hence the design...

This paper describes the application of an evolutionary optimization method to design satellite constellation for continuous regional coverage without intersatellite links. This configuration, called mutual coverage, is related to some technical limitations that exist on small satellite technology. The coverage of the north Algerian seismological network is taken as an example of application. A...