BACKGROUND Prolonged mechanical ventilation is associated with muscle weakness, pharyngeal dysfunction, and symptomatic aspiration. The authors hypothesized that muscle strength measurements can be used to predict pharyngeal dysfunction (endoscopic evaluation-primary hypothesis), as well as symptomatic aspiration occurring during a 3-month follow-up period. METHODS Thirty long-term ventilated...

The diagnosis of paralytic poliomyelitis is now rarely considered in cases ofacute lower motor neurone weakness in patients resident in Britain. Paralytic poliomyelitis still occurs,' however, and we report two cases, one of which would not have occurred had the present immunisation procedures been followed. The occurrence of the other case suggests that immunisation procedures should be modifi...

background: fear of falling is not only a risk factor for falls, but it is also an important clinical predictor of functional decline in older adults. this study identified sex differences in fear of falling and related factors in older adults with low grip strength. methods: the data of 902 older adults from the 2012 korean national survey, conducted as a research project by the korea employme...

how to cite this article: tonekaboni s.h. juvenile pompe. iran j child neurol autumn 2012; 6:4 (suppl. 1):10.   pls see pdf.

background: diseases that cause acute flaccid paralysis (afp) often progress rapidly, thus may cause life threatening complications, therefore, their diagnosis and cure are important. this study was carried out to investigate the causes of acute generalized weakness in children referred to amirkola children’s hospital, in babol, iran. methods: in this case series, the epidemiological causes of ...

background: interferons (ifns) are common therapeutics for several diseases such as viral hepatitis, multiple sclerosis and malignancy. a variety of autoimmune related side effects have been observed during ifn therapy. rare cases of myopathy, polymyositis or dermatomyositis have been reported during therapy with high doses of ifn^5. case presentation: in this report, we describe a case with se...

how to cite this article : aminzadeh v, hassanzadeh rad a. a report of guillain–barré syndrome with myalgiaand mild weakness. iran j child neurol. 2014 spring; 8(2):70-72.   we report a rare case that revealed severe myalgia as the chief complaint that is not mentioned in the list of frequent symptoms of guillain barré. guillain-barré syndrome (gbs) is an acute inflammatory demyelinating polyne...

kennedy disease is a rare x-linked neurodegenerative disorder that affects patients in 30-50 years of age. it is caused by cag-repeat in androgen receptor gen. there is no known effective treatment for kennedy disease. we report a 60-year-old man who had fasciculations and proximal and distal muscle weakness. physical examination showed involvement of the bulbar musculature accompanied by tongu...

BACKGROUND Although muscle weakness is a hallmark of facioscapulohumeral muscular dystrophy (FSHD), the molecular mechanisms that lead to weakness in FSHD remain largely unknown. Recent studies suggest aberrant expression of genes involved in skeletal muscle development and sarcomere contractility, and activation of pathways involved in sarcomeric protein degradation. This study will investigat...