Genetically modified organisms (GMOs), e.g. viral vectors, could threaten the environment if by their release they spread hazardous gene products. Even in contained use, to prevent adverse consequences, viral vectors carrying genes from mammals or humans should be especially scrutinized as to whether gene products that they synthesize could be hazardous in their new context. Examples of such po...

Polymorphisms of human TCR gene products have been suggested by the description of a mAb, OT145, that identifies a subset of TCRs in some individuals but not in others (6). Here we demonstrate that this mAb detects a TCR allotype of the V beta 6.7 gene. Two allelic products of this V gene differ by two nonconservative amino acid substitutions. The mAb OT145 appears to react with V beta 6.7 a ge...

The possibilities of nutrigenomics as an approach to determining the effectiveness specialized food products have been studied. For this purpose, influence consumption whey protein concentrate FitPROTEIN and carrier branched-chain amino acids SPORTAMIN®BCAA 6000 on expression target gene FTO was determined. Despite a certain similarity in composition these products, their effect average level i...

A large number of biological pathways have been elucidated recently, and there is a need for methods to analyze these pathways. One class of methods compares pathways semantically in order to discover parts that are evolutionarily conserved between species or to discover intraspecies similarities. Such methods usually require that the topologies of the pathways being compared are known, i.e. th...

calpastatin has been introduced as an effective candidate gene as regards growth efficiency and meat quality traits. throughout the present study, blood sampling as well as carcass trait measurements were performed on 74 lori-bakhtiari sheep and on 40 zel-atabay cross-breds from industrial slaughterhouses of shahrekord and gorgan cities, respectively. following dna extaction, polymerase chain r...