adenosine deaminase (ada) is an important regulator of insulin action. the single nucleotide polymorphism (snp) g22a in the ada gene decreases enzymatic activity of ada. the aim of this study was to investigate the relationship between the snp g22a and blood glycemic control, insulin resistance, and obesity of gestational diabetes mellitus (gdm) patients in an iranian population. snp g22a was d...

AIMS/INTRODUCTION To observe the longitudinal changes in serum adipocyte fatty acid-binding protein (AFABP), carbohydrate, and lipid metabolism parameters in women with and without gestational diabetes mellitus (GDM) during mid- and late pregnancy periods, as well as to identify whether there is any association between AFABP and development of GDM. MATERIALS AND METHODS A total of 40 GDM and ...

OBJECTIVE Gestational diabetes mellitus (GDM) is a known harbinger of future type 2 diabetes mellitus (T2DM), hypertension, and cardiac disease. This population-based study was designed to identify gaps in follow-up care relevant to prevention of T2DM in a continuously insured sample of women diagnosed with GDM. RESEARCH DESIGN AND METHODS We analyzed data spanning 2005-2015 from OptumLabs Da...

OBJECTIVE Infants born to mothers with gestational diabetes mellitus (GDM) are at greater risk of later adverse metabolic health. We examined plausible candidate mediators, adipose tissue (AT) quantity and distribution and intrahepatocellular lipid (IHCL) content, comparing infants of mothers with GDM and without GDM (control group) over the first 3 postnatal months. RESEARCH DESIGN AND METHO...

Catalano, Patrick M, Steven E. Nizielski, Jianhua Shao, Larraine Preston, Liping Qiao, and Jacob E. Friedman. Downregulated IRS-1 and PPAR in obese women with gestational diabetes: relationship to FFA during pregnancy. Am J Physiol Endocrinol Metab 282: E522–E533, 2002. First published November 6, 2001; 10.1152/ajpendo.00124. 2001.—Gestational diabetes mellitus (GDM) is associated with elevated...

OBJECTIVE The aim of this study was to investigate the prevalence of gestational diabetes mellitus (GDM) and risk factors for the development of GDM in pregnant women in Tianjin, China, where the prevalence of GDM is still unknown. STUDY DESIGN AND METHODS A total of 9,471 pregnant women living in the six urban districts of Tianjin, China, took part in the initial screening between December 1...

Address for Correspondence: Ms. P. Sharmila Bhanu, Department of Anatomy, Narayana Medical College, Chinthareddy Palem, Nellore, Andhra Pradesh 524002, India. Mobile: +91-9441705457 Fax: +91-861-2317962 E-Mail: [email protected] Introduction: Gestational diabetes mellitus (GDM) is an ever increasing threat in Indian women, is found up to 10% of the total pregnancies and is mainly due to di...

OBJECTIVE Gestational diabetes mellitus (GDM) is associated with fetal macrosomia and maternal postpartum dysglycemia, insulin resistance, and β-cell dysfunction. Indeed, in practice, a prior pregnancy that resulted in a large-for-gestational-age (LGA) delivery is often considered presumptive evidence of GDM, whether or not it was diagnosed at the time. If this clinical assumption is correct, h...

BACKGROUND Overweight/obese (OW/OB) women are at high risk to develop gestational diabetes mellitus (GDM) in pregnancy. AIM To investigate, in pregnant OW/OB women, the longitudinal changes of adiponectin plasma levels, carbohydrate and lipid metabolism, and to identify if there is any association between adipokines and subsequent development of GDM. SUBJECTS AND METHODS Thirty-two OW/OB no...